A METHOD FOR PREPARATION OF DROSERONE FROM PLUMBAGIN
Keyword(s):
13C Nmr
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Droserone (2,5-dihyrdoxy-3-methyl-1,4- naphthoquinone) was prepared from naturally occurring naphthoquinone plumbagin. Plumbagin was isolated from roots of Plumbago zeylanica. Plumbagin was first brominated at C-3 which was subsequently substituted with hydroxy group by a nucleophilic substitution to obtain Droserone. The synthesized compounds were characterized by IR, MS, 1H and 13C NMR spectral data. RP-HPLC was used to ascertain the purity of the obtained compound.
1990 ◽
Vol 55
(5)
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pp. 1208-1215
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1992 ◽
Vol 48
(10)
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pp. 1347-1353
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Correlation analysis of IR, 1H and 13C NMR spectral data of N-alkyl and N-cycloalkyl cyanoacetamides
2011 ◽
Vol 17
(3)
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pp. 307-314
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