Phyto-Pharmacognostical Standardization with HPTLC Fingerprinting of Root of Citraka (Plumbago Zeylanica L.)

Background: Citraka or Sveta Citraka (Plumbago zeylanica L.) is an important medicinal plant mentioned in Ayurvedic classics, belongs to the family Plumbaginaceae. The root of the plant exhibits medicinal properties. It has a broad range of pharmacological activities, including anti-inflammatory, antibacterial, antifungal, anticancer, antidiabetic, antioxidant, hepatoprotective, wound healing and cytotoxic. Objective: The aim of the study was to evaluate phyto-pharmacognostical standardization with HPTLC fingerprinting of root of P. zeylanica, one of the most accepted and beneficial medicinal plant in Ayurveda. Materials and Methods: P. zeylanica was collected from Konni, Kerala, India during the month of May 2018 and its root was studied for macroscopic, microscopic, physico-chemical, preliminary phytochemical screening and HPTLC fingerprinting following the standard protocol recommended by The Ayurvedic Pharmacopoeia of India and Quality Standards of Indian Medicinal Plants. Results: The root is long, stout, cylindrical and reddish to dark brown in colour. The transverse section of root showed 5-7 rows of small cubical or rectangular celled cork with light yellow walls, polygonal or slightly tangentially elongated cortex cells containing starch grains and coloured contents, phloem containing small groups of fibres, radially arranged xylem vessels and narrow, 1-4 seriate medullary rays. Physico-chemical analysis showed water soluble extractive value as 26.11±0.01 w/w and alcohol soluble extractive value as 15.85±0.00 w/w. Preliminary phytochemical analysis of root decoction showed the presence of alkaloids, carbohydrates, tannins, saponins, resin and quinones. Conclusion: The information obtained from this research work may be useful to establish the botanical as well as analytical standards for the root of P. zeylanica.

A Comprehensive Review on Anti-Inflammatory Activity of The Traditional Plants Plumbago zeylanica(Chitra)

Medicinal plants have long been utilised as a source of medicine and are in high demand throughout the world. They've been around for a long time, and they've been utilised to cure and prevent ailments. Plumbago zeylanica is a medicinal plant that is frequently utilised for its medicinal properties. It contains several bioactive compounds like napthoquinones, flavonoids, alkaloids, glycosides, steroids, tri-terpenoids, tannins, fixed oils, fats, proteins, etc. among all plumbagin is most important bioactive compounds. It possesses wide range of pharmaceutical activities such as anti-inflammatory, antimicrobial, anti-cancer, anti-ulcer, antidiabetic etc. Several investigations on its pharmacological activity have been conducted. The goal of this review is to provide a comprehensive understanding of P. zeylanica's chemical composition and pharmacological action.