Thermodynamic activity-based enzyme kinetics: Efficient tool for nonaqueous enzymology

AIChE Journal ◽  
2001 ◽  
Vol 47 (3) ◽  
pp. 718-726 ◽  
Author(s):  
Georgina C. Sandoval ◽  
Alain Marty ◽  
Jean-Stéphane Condoret
Keyword(s):  
Enzyme Kinetics ◽  
Thermodynamic Activity ◽  
Efficient Tool ◽  
Nonaqueous Enzymology

Kinetic Aspects of the Interaction of Blood Clotting Enzymes

1968 ◽  
Vol 19 (03/04) ◽  
pp. 364-367 ◽  
Author(s):  
H. C Hemker ◽  
P. W Hemker
Keyword(s):  
Enzyme Kinetics ◽  
Blood Clotting ◽  
Competitive Inhibition ◽  
Competitive Inhibitor ◽  
Kinetics Of

SummaryThe enzyme kinetics of competitive inhibition under conditions prevailing in clotting tests are developed and a method is given to measure relative amounts of a competitive inhibitor by means of the t — D plot.

Kinetic Aspects of the Interaction of Blood Clotting Enzymes

1965 ◽  
Vol 13 (01) ◽  
pp. 155-175 ◽  
Author(s):  
H. C Hemker ◽  
P.W Hemker ◽  
E. A Loeliger
Keyword(s):  
Kinetic Analysis ◽  
Enzyme Kinetics ◽  
Blood Clotting ◽  
Enzyme System ◽  
Enzyme Kinetic ◽  
Clotting Time ◽  
Standard Methods

SummaryApplication of the methods of enzyme-kinetic analysis to the results of clotting tests is feasible and can yield useful results. However, the standard methods of enzyme kinetics are not applicable without modifications imposed by the peculiarities of the blood-clotting enzyme system. The influence of the following complicating circumstances is calculated :1. Substrate is not present in excess.2. Only relative measures exist for concentrations of substrate or enzymes.3. Enzymes and substrates are often added together.4. Reagents are not pure.5. Clotting-time is our only measure for clotting-velocity.Formulas are deduced, which makes it possible to recognize the effect of these complications.

1151-P: Dorzagliatin Differentiates from Early Generation of Glucokinase Activators: An Enzyme Kinetics Study

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1151-P
Author(s):  
LI CHEN ◽  
YONGQIANG SHAN ◽  
XIAOWEI JIN ◽  
XIAOBING LV
Keyword(s):  
Enzyme Kinetics ◽  
Kinetics Study ◽  
Early Generation ◽  
Glucokinase Activators

Analysis of Remote Sensing based Vegetation Indices (VIs) for Unmanned Aerial System (UAS): A Review

2020 ◽  
Vol 3 (2) ◽  
pp. 58-73
Author(s):  
Vijay Bhagat ◽  
Ajaykumar Kada ◽  
Suresh Kumar
Keyword(s):  
Remote Sensing ◽  
Spatial Data ◽  
Satellite Remote Sensing ◽  
Vegetation Indices ◽  
Unmanned Aerial System ◽  
Sustainable Land Management ◽  
Efficient Tool ◽  
Site Specific ◽  
The Earth ◽  
Interesting Area

Unmanned Aerial System (UAS) is an efficient tool to bridge the gap between high expensive satellite remote sensing, manned aerial surveys, and labors time consuming conventional fieldwork techniques of data collection. UAS can provide spatial data at very fine (up to a few mm) and desirable temporal resolution. Several studies have used vegetation indices (VIs) calculated from UAS based on optical- and MSS-datasets to model the parameters of biophysical units of the Earth surface. They have used different techniques of estimations, predictions and classifications. However, these results vary according to used datasets and techniques and appear very site-specific. These existing approaches aren’t optimal and applicable for all cases and need to be tested according to sensor category and different geophysical environmental conditions for global applications. UAS remote sensing is a challenging and interesting area of research for sustainable land management.

An Efficient Tool for Searching Maximal and Super Maximal Repeats in Large DNA/Protein Sequences via Induced-Enhanced Suffix Array

2019 ◽  
Vol 12 (2) ◽  
pp. 128-134
Author(s):  
Sanjeev Kumar ◽  
Suneeta Agarwal ◽  
Ranvijay
Keyword(s):  
Protein Sequences ◽  
Input Sequence ◽  
Suffix Array ◽  
Secondary Memory ◽  
Time And Space ◽  
Efficient Tool ◽  
Frequency Distributions ◽  
Alignment Algorithms ◽  
Common Prefix ◽  
Art Works

Background: DNA and Protein sequences of an organism contain a variety of repeated structures of various types. These repeated structures play an important role in Molecular biology as they are related to genetic backgrounds of inherited diseases. They also serve as a marker for DNA mapping and DNA fingerprinting. Efficient searching of maximal and super maximal repeats in DNA/Protein sequences can lead to many other applications in the area of genomics. Moreover, these repeats can also be used for identification of critical diseases by finding the similarity between frequency distributions of repeats in viruses and genomes (without using alignment algorithms). Objective: The study aims to develop an efficient tool for searching maximal and super maximal repeats in large DNA/Protein sequences. Methods: The proposed tool uses a newly introduced data structure Induced Enhanced Suffix Array (IESA). IESA is an extension of enhanced suffix array. It uses induced suffix array instead of classical suffix array. IESA consists of Induced Suffix Array (ISA) and an additional array-Longest Common Prefix (LCP) array. ISA is an array of all sorted suffixes of the input sequence while LCP array stores the lengths of the longest common prefixes between all pairs of consecutive suffixes in an induced suffix array. IESA is known to be efficient w.r.t. both time and space. It facilitates the use of secondary memory for constructing the large suffix-array. Results: An open source standalone tool named MSR-IESA for searching maximal and super maximal repeats in DNA/Protein sequences is provided at https://github.com/sanjeevalg/MSRIESA. Experimental results show that the proposed algorithm outperforms other state of the art works w.r.t. to both time and space. Conclusion: The proposed tool MSR-IESA is remarkably efficient for the analysis of DNA/Protein sequences, having maximal and super maximal repeats of any length. It can be used for identification of well-known diseases.

Valence states of atoms and their conversions

1984 ◽  
Vol 49 (5) ◽  
pp. 1247-1261 ◽  
Author(s):  
Jaroslav Koča ◽  
Milan Kratochvíl ◽  
Milan Kunz ◽  
Vladimír Kvasnička
Keyword(s):  
Chemical Reactions ◽  
Computer Assisted ◽  
Efficient Tool ◽  
Common Features ◽  
Systematic Application ◽  
Organic Syntheses ◽  
Valence States ◽  
Algebraic Formalism

The algebraic formalism for the description of valence states of atoms and their interconversions is elaborated. It offers a possibility to construct and trace mechanistic paths of chemical reactions, the problem of which is of great importance in computer-assisted organic syntheses. Its systematic application gives exhaustive lists of possible mechanistic paths, and furthermore, very efficient tool to classify chemical reactions and look for their common features.

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