Photochemical and electrochemical strategies in C-F bonds activation and functionalization

The activation and functionalization of C-F bonds under mild conditions can serve as an important tool for organic syntheses including the modification of pharmaceuticals or agrochemicals and the synthesis of...

Application of Metal Halide Perovskites as Photocatalysts in Organic Reactions

This review summarizes the current status of the application of metal halide perovskites (MHPs) as photocatalysts in organic syntheses/transformations. It is shown that the optimal and unique electronic properties of MHPs can be advantageously used in several reaction types providing pros with respect to traditional photocatalysts. While still being at infancy, such field of application of MHPs as effective photocatalysts will for sure become a central research topic in the forthcoming years, thanks also to their rich structural and chemical tunability, which may provide tailored materials for most of the envisaged organic reactions.

Application of industrially relevant HFO gases in organic syntheses

Hydrofluoroolefin (HFO) gases are state-of-the-art cooling agents with widespread household and industrial applications. Considering their structural benefits these fluorous feedstocks gained attention of organic chemists in the last couple of years. In this short review we summarized the existing synthetic transformations of these gaseous starting material and present their applicability in the synthesis of fluorine containing organic molecules, which have potential importance as building blocks and reagents for diverse syntheses.

Recent advances in synthesis and reactions of β-amino-α,β-enones (enaminones)

β-Amino-α,β-enones or β-enamino carbonyl compounds are versatile synthons intermediates for the construction of various bio-active heterocyclic compounds and have been established as multipurpose synthetic precursors in organic syntheses and in pharmaceutical developments. In this work, we will discuss the different synthetic routes to obtain β-Amino-α,β-enones or β-enamino carbonyl compounds, their reactions, and their utility in the construction of organic frameworks and heterocyclic ring systems. Structurally, β-amino-α,β-enones are attractive intermediates that syndicate the ambident behaviours of nucleophilicity and electrophilicity of enones simultaneously. β-amino-α,β-enones have been known as acceptors in both 1,2- and 1,4- additions, which make them good intermediate compounds for annulation to different heterocycles.

A comprehensive insight into aldehyde deformylation: mechanistic implications from biology and chemistry

Aldehyde deformylation is one of the useful reactions in biology and organic syntheses and this review provides mechanistic insights into the same.

Organic syntheses greenness assessment with multicriteria decision analysis

Green chemistry requires the metrics system that are comprehensive by the criteria included and simple in application at the same time. We propose the application of multicriteria decision analysis for...

α-C-H functionalizations of tertiary amines catalyzed/promoted by molecular iodine/derivatives

This review article focuses on the functionalization of α-C-H bond of tertiary amines via C-H activation catalyzed by iodine or its derivatives. Recently, transition metal-free C-H functionalizations in organic syntheses...