Identification and characterization of a complex pure mosaic of small supernumerary marker chromosomes involving 11p11.12 → q12.1 and 19p12 → q12 regions in a child featuring multiple congenital anomalies

2011 ◽  
Vol 155 (12) ◽  
pp. 3116-3121 ◽  
Author(s):  
Xiang Fei ◽  
Manlong Qi ◽  
Yanyan Zhao ◽  
Jesse Li-Ling
Keyword(s):  
Congenital Anomalies ◽  
Multiple Congenital Anomalies ◽  
Marker Chromosomes ◽  
Identification And Characterization ◽  
Small Supernumerary Marker Chromosomes ◽  
Supernumerary Marker Chromosomes

Characterization of three small supernumerary marker chromosomes (sSMC) in humans

2012 ◽  
Vol 26 (1) ◽  
pp. 106-108 ◽  
Author(s):  
Jian Ou ◽  
Wei Wang ◽  
Thomas Liehr ◽  
Elisabeth Klein ◽  
Ahmed B. Hamid ◽  
...  
Keyword(s):  
Marker Chromosomes ◽  
Small Supernumerary Marker Chromosomes ◽  
Supernumerary Marker Chromosomes

scholarly journals Characterization of Small Supernumerary Marker Chromosomes By A Simple Molecular and Molecular Cytogenetics Approach

2007 ◽  
Vol 10 (1) ◽  
pp. 33-37 ◽  
Author(s):  
T Liehr ◽  
V Trifonov ◽  
A Polityko ◽  
L Brecevic ◽  
K Mrasek ◽  
...  
Keyword(s):  
Molecular Cytogenetics ◽  
Metaphase Spread ◽  
Marker Chromosomes ◽  
Chromosomal Origin ◽  
Chromosome 20 ◽  
Small Supernumerary Marker Chromosomes ◽  
Supernumerary Marker Chromosomes

Characterization of Small Supernumerary Marker Chromosomes By A Simple Molecular and Molecular Cytogenetics ApproachSmall supernumerary marker chromosomes (sSMC) are still a major problem especially in prenatal cytogenetic diagnostics and counseling. These structurally abnormal chromosomes cannot be identified or characterized unambiguously by conventional banding cytogenetics alone, and are generally about the size of or smaller than a chromosome 20 in the same metaphase spread. We describe a straightforward algorithm, based on data from 2,211 reported cases (http://www.markerchromosomes.ag.vu) to quickly characterize the sSMC's chromosomal origin.

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