Autism and serotonin transporter gene polymorphisms: A systematic review and meta-analysis

2008 ◽  
Vol 147B (6) ◽  
pp. 903-913 ◽  
Author(s):  
Christine H. Huang ◽  
Susan L. Santangelo
2002 ◽  
Vol 7 (1) ◽  
pp. 67-71 ◽  
Author(s):  
C Betancur ◽  
◽  
M Corbex ◽  
C Spielewoy ◽  
A Philippe ◽  
...  

2003 ◽  
Vol 28 (3) ◽  
pp. 446-458 ◽  
Author(s):  
J. Melke ◽  
L. Westberg ◽  
M. Landén ◽  
C. Sundblad ◽  
O. Eriksson ◽  
...  

2003 ◽  
Vol 18 (2) ◽  
pp. 77-81 ◽  
Author(s):  
Hasan Herken ◽  
M. Emin Erdal ◽  
Ömer Böke ◽  
Haluk A. Savaş

AbstractBackgroundThe pathophysiology of tardive dyskinesia (TD) is not completely understood.AimTo assess the relationship of TD with 5-HT2A receptor gene, serotonin transporter gene (5 HTT), and catechol-o-methyltransferase (COMT) gene polymorphisms.MethodsOur study comprised 111 unrelated subjects who strictly met DSM-IV criteria for schizophrenia and 32 TD, and 79 healthy unrelated controls; all the subjects were of Turkish origin. The analyses of 5-HT2A receptor gene, 5 HTT gene, and COMT gene polymorphisms were performed using polymerase chain reaction (PCR) technique.ResultsThe polymorphisms of these genes were not significantly different between the schizophrenic patients, TD and control subjects.ConclusionsOur findings indicated that 5-HT2A receptor gene, 5 HTT gene, and COMT gene polymorphisms were similar in schizophrenia with non-TD, schizophrenia with TD, and healthy controls. These polymorphisms, though, do not help to evaluate the susceptibility to TD.


Sign in / Sign up

Export Citation Format

Share Document