Abstract
Objectives:To examine the responsiveness, reliability, and validity of Chinese version of Systemic Lupus Erythematosus Questionnaire (SLAQ). Methods:A cross-sectional observational study was designed for this research. The principal attributes evaluated were linguistic and cultural adaption, reliability, and validity.Standardized response means and acceptability were calculated to estimate the responsiveness of the SLAQ. Cronbach’s alpha was used to evaluate its reliability. The Spearman correlation coefficient was used to assess the criterion validity by calculating the association with measurement of other lupus disease activity.ResultsThe response rate for the pilot study was 99.9%. The mean time to complete the questionnaire was 6.7±2.8 min. The Chinese version of SLAQ had good reliability, with a Cronbach’s alpha of 0.857. Cronbach’s alpha for the test-retest reliability was 0.878. For validity, the SLAQ was correlated with SLAM, SLEDAI-2000 and SLEDAI-no lab. The correlation was good at 0.832, 0.506 and 0.668 respectively.Conclusion:The Chinese version of the SLAQ questionnaire has adequate responsiveness, reliability, and validity in our cohort, and it is a helpful and meaningful tool for assessing disease activity in lupus patients without laboratory results.
Reliability and validity of six systems for the clinical assessment of disease activity in systemic lupus erythematosus