Local analgesia: Head and neck. By Sir Robert Macintosh, D.M., F.R.C.S. (Edin.), F.F.A.R.C.S., Nuffield Professor of Anæsthetics, University of Oxford; Mary Ostlere, M.B., M.R.C.P.E., F.F.A.R.C.S., Research Assistant, Nuffield Department of Anæsthetics, University of Oxford. 8 5/8 × 5 7/8 in. Pp. 138 + viii, with 145 illustrations by Marjorie Beck, some coloured. 1955. Edinburgh: E. & S. Livingstone Ltd. 27s. 6d

1956 ◽  
Vol 43 (180) ◽  
pp. 446-446
Keyword(s):  
Head And Neck ◽  
Local Analgesia ◽  
Research Assistant ◽  
University Of Oxford ◽  
Nuffield Department

PRODUCTION OF THROMBOXANE B2 BY INTRA-UTERINE TISSUES FROM PREGNANT GOATS IN VITRO

1978 ◽  
Vol 78 (1) ◽  
pp. 159-160 ◽  
Author(s):  
M. D. MITCHELL ◽  
A. P. F. FLINT ◽  
E. J. KINGSTON ◽  
G. D. THORBURN ◽  
J. S. ROBINSON
Keyword(s):  
Thromboxane B2 ◽  
Basic Data ◽  
University Of Oxford ◽  
Obstetrics And Gynaecology ◽  
Nuffield Department ◽  
John Radcliffe Hospital ◽  
Prostaglandin F ◽  
Prostaglandins E

Nuffield Department of Obstetrics and Gynaecology, University of Oxford, John Radcliffe Hospital, Headington, Oxford, OX3 9DU (Received 9 February 1978) It has been shown that prostaglandins play an important role in the mechanism of parturition in many species, including the goat (Currie & Thorburn, 1977; Thorburn, Challis & Robinson, 1977). Recently we have demonstrated that intra-uterine tissues from pregnant goats, when superfused in vitro, produce prostaglandins E and F (PGE, PGF) and 13,14-dihydro-15-oxo-prostaglandin F at various rates (Mitchell, Flint, Robinson & Thorburn, 1978). The exciting discoveries of two potent prostaglandin-like compounds, thromboxane A2 (TXA2; Hamberg, Svensson & Samuelsson, 1975) and prostacyclin (PGI2; Moncada, Gryglewski, Bunting & Vane, 1976), have radically altered our thinking on prostaglandins and basic data are urgently required concerning these compounds. Since prostaglandin endoperoxides are the immediate precursors of both prostaglandins and TXA2 (and PGI2) and since TXA2 has been shown to cause contraction of a number

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