scholarly journals Distinct MRI pattern of “pseudoresponse” in recurrent glioblastoma multiforme treated with regorafenib: Case report and literature review

2021 ◽  
Vol 9 (8) ◽  
Author(s):  
Lidia Gatto ◽  
Enrico Franceschi ◽  
Alicia Tosoni ◽  
Vincenzo Di Nunno ◽  
Ilaria Maggio ◽  
...  
Author(s):  
Csaba Tóth ◽  
Andrea Dabóczi ◽  
Madhvi Chanrai ◽  
Mária Schimmer ◽  
Katalin Horváth ◽  
...  

Studies in animal models have suggested that the ketogenic diet may be effective in the treatment of cancer. However, human cohort studies on the ketogenic diet have, thus far, failed to show benefits in cancer survival or in any other hard clinical endpoints of the disease. This paper presents a case report of a patient with glioblastoma multiforme. The patient had initially been treated with standard oncotherapy including surgery, radiotherapy and chemotherapy. Despite standard treatment, the patient experienced a recurrence of the glioblastoma seven months later. Subsequently, the patient refused radiotherapy and chemotherapy and opted to use the paleolithic ketogenic diet (PKD) as a stand-alone therapy. Following the adoption of the PKD, progression of the disease has been completely halted. At the time of writing, the patient has remained in remission for 48 months, is without side-effects and experiences an excellent quality of life without the use of any drugs.


Author(s):  
Csaba Tóth ◽  
Andrea Dabóczi ◽  
Madhvi Chanrai ◽  
Mária Schimmer ◽  
Zsófia Clemens

Studies in animal models have suggested that the ketogenic diet may be effective in the treatment of cancer. However, human cohort studies on the ketogenic diet have, thus far, failed to show benefits in cancer survival or in any other hard clinical endpoints of the disease. This paper presents a case report of a patient with glioblastoma multiforme. The patient had initially been treated with standard oncotherapy including surgery, radiotherapy and chemotherapy. Despite standard treatment, the patient experienced a recurrence of the glioblastoma seven months later. Subsequently, the patient refused radiotherapy and chemotherapy and opted to use the paleolithic ketogenic diet (PKD) as a stand-alone therapy. Following the adoption of the PKD, progression of the disease has been completely halted. At the time of writing, the patient has remained in remission for 38 months, is without side-effects and experiences an excellent quality of life without the use of any drugs.


2011 ◽  
Vol 5 ◽  
pp. CMO.S6525 ◽  
Author(s):  
Abhirami Vivekanandarajah ◽  
Balakumar Krishnarasa ◽  
Mervat Mourad ◽  
Nelly Aoun ◽  
Marcel Odaimi

A 34-year-old man presented to the hospital with right-sided headache. He was diagnosed with GBM. He underwent resection of the tumor with placement of carmustine impregnated wafers. Then he underwent adjuvant chemotherapy with temozolamide. Before the completion of chemotherapy he had a recurrence. He underwent re-resection with placement of carmustine impregnated wafers. Subsequently he had eighteen cycles of salvage biochemotherapy with bevacizumab and irinotecan. To date, routine MRI scans of the brain have not shown evidence of recurrence. He continues to be in remission three years after treatment with bevacizumab and irinotecan.


2002 ◽  
Vol 13 (5) ◽  
pp. 777-780 ◽  
Author(s):  
C. Twelves ◽  
M. Campone ◽  
B. Coudert ◽  
M. Van den Bent ◽  
M. de Jonge ◽  
...  

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