ChemInform Abstract: SUBSTANCES WITH ANTINEOPLASTIC ACTIVITY PART 53, N-(DELTA-(4-PYRROLO(2,3-D)PYRIMIDINYLTHIO)-VALERYL)-AMINO ACIDS AND ANALOGOUS DERIVATIVES OF DI- AND TRIGLYCINE

1973 ◽  
Vol 4 (34) ◽  
pp. no-no
Author(s):  
R. KOTVA ◽  
A. CERNY ◽  
M. SEMONSKY
Keyword(s):  
Amino Acids ◽  
Antineoplastic Activity ◽  
Derivatives Of

Some 2-substitution derivatives of 5-(4-oxo-6-hydroxy-3,4-dihydro-5-pyrimidinyl)pentanoic acid

1983 ◽  
Vol 48 (1) ◽  
pp. 304-311 ◽  
Author(s):  
Jiří Křepelka ◽  
Jan Beneš ◽  
Vladimír Pouzar ◽  
Jaroslav Vachek ◽  
Jiří Holubek
Keyword(s):  
Nitrile Group ◽  
Antineoplastic Activity ◽  
Carboxyl Group ◽  
Positional Isomers ◽  
Pentanoic Acid ◽  
Pharmacological Tests ◽  
Derivatives Of

Condensation of triethyl ester of 1,1,5-pentanetricarboxylic acid (XI) with substituted guanidines XXII - XXIX gave acids II - IX, which were converted into esters XI - XIX. The acid II and the ester XI were obtained as mixtures of positional isomers. Analogously, condensation of the triester XXI with dicyanodiamide gave rise to acid X, whose nitrile group, under conditions of esterification of a carboxyl group, produced iminoether XX. In pharmacological tests for antineoplastic activity the compounds prepared exhibited weaker efficacy than 5-(2-amino-6-hydroxy-4-oxo-3,4-dihydro-5-pyrimidinyl)pentanoic acid (I), employed as standard.

Derivatives of aminoquinones with N-protected amino acids

1998 ◽  
Vol 5 (4) ◽  
pp. 259-262 ◽  
Author(s):  
Chrysostomos Pachatouridis ◽  
Elias A. Couladouros ◽  
Vassilios P. Papageorgiou ◽  
Maria Liakopoulou-Kyriakides
Keyword(s):  
Amino Acids ◽  
Derivatives Of

Pentacarbonyl complexes of tungsten with derivatives of amino acids

1984 ◽  
Vol 33 (7) ◽  
pp. 1539-1539
Author(s):  
A. A. Ioganson ◽  
Yu. G. Kovalev ◽  
L. L. Milovanova
Keyword(s):  
Amino Acids ◽  
Derivatives Of
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