ChemInform Abstract: Highly Stereoselective and General Synthesis of Z-3-Methyl-2-alken-1- ols via Palladium-Catalyzed Cross Coupling of Z-3-Iodo-2-buten-1-ol with Organozincs and Other Organometals.

ChemInform ◽  
2010 ◽  
Vol 24 (28) ◽  
pp. no-no
Author(s):  
E. NEGISHI ◽  
M. AY ◽  
Y. V. GULEVICH ◽  
Y. NODA
Keyword(s):  
Cross Coupling ◽  
Palladium Catalyzed ◽  
General Synthesis

scholarly journals Palladium-Catalyzed Cross-Coupling Between Vinyl Halides and tert-Butyl Carbazate: First General Synthesis of the Unusual N-Boc-N-alkenylhydrazines.

ChemInform ◽  
2007 ◽  
Vol 38 (18) ◽  
Author(s):  
Jose Barluenga ◽  
Patricia Moriel ◽  
Fernando Aznar ◽  
Carlos Valdes
Keyword(s):  
Cross Coupling ◽  
Tert Butyl ◽  
Vinyl Halides ◽  
Palladium Catalyzed ◽  
General Synthesis

The directed ortho metalation - palladium catalyzed cross coupling connection. A general regiospecific route to 9-phenanthrols and phenanthrenes. Exploratory further metalation

2000 ◽  
Vol 78 (6) ◽  
pp. 905-919 ◽  
Author(s):  
Jian-min Fu ◽  
Victor Snieckus
Keyword(s):  
Cross Coupling ◽  
Ring Contraction ◽  
Ortho Metalation ◽  
Palladium Catalyzed ◽  
General Synthesis

A new general and regiospecific synthesis of 9-phenanthrols (1 +2 [Formula: see text] 3 [Formula: see text] 4, Scheme 1, Table 1) proceeding by a Directed ortho Metalation (DoM), Suzuki-Miyaura cross coupling, and a new LDA-mediated Directed remote Metalation sequence is described. The facile Pd-catalyzed hydrogenolysis of the phenanthrols 4 into the corresponding phenanthrenes 5 via their triflates 18 translates the original DoM regioselectivity also into a general synthesis of phenanthrenes (Table 2). Further DoM (19 [Formula: see text]20, 21; 24 [Formula: see text]25), cross coupling (20c [Formula: see text]23), as well as oxidation - ring contraction (4b, 4f [Formula: see text]28a, 28b) chemistry of phenanthrene derivatives is reported.Key words: 9-phenanthrols, directed ortho metalation, Suzuki cross coupling, synthesis.

ChemInform Abstract: General Synthesis of Retinoids and Arotinoids via Palladium-Catalyzed Cross-Coupling of Boronic Acids with Electrophiles.

ChemInform ◽  
2010 ◽  
Vol 26 (44) ◽  
pp. no-no
Author(s):  
A. TORRADO ◽  
S. LOPEZ ◽  
R. ALVAREZ ◽  
A. R. DE LERA
Keyword(s):  
Cross Coupling ◽  
Boronic Acids ◽  
Palladium Catalyzed ◽  
General Synthesis

General Synthesis of Retinoids and Arotinoids via Palladium-Catalyzed Cross-Coupling of Boronic Acids with Electrophiles

Synthesis ◽  
1995 ◽  
Vol 1995 (03) ◽  
pp. 285-293 ◽  
Author(s):  
Alicia Torrado ◽  
Susana López ◽  
Rosana Alvarez ◽  
Angel R. de Lera
Keyword(s):  
Cross Coupling ◽  
Boronic Acids ◽  
Palladium Catalyzed ◽  
General Synthesis

Palladium-Catalyzed Cross-Coupling between Vinyl Halides andtert-Butyl Carbazate:  First General Synthesis of the UnusualN-Boc-N-alkenylhydrazines

2007 ◽  
Vol 9 (2) ◽  
pp. 275-278 ◽  
Author(s):  
José Barluenga ◽  
Patricia Moriel ◽  
Fernando Aznar ◽  
Carlos Valdés
Keyword(s):  
Cross Coupling ◽  
Vinyl Halides ◽  
Palladium Catalyzed ◽  
General Synthesis

Highly stereoselective and general synthesis of (z)-3-methyl-2-alken-1-ols via palladium-catalyzed cross coupling of (z)-3-iodo-2-buten-1-ol with organozincs and other organometals

1993 ◽  
Vol 34 (9) ◽  
pp. 1437-1440 ◽  
Author(s):  
Ei-ichi Negishi ◽  
Mehmet Ay ◽  
Yuri V. Gulevich ◽  
Yumiki Noda
Keyword(s):  
Cross Coupling ◽  
Palladium Catalyzed ◽  
General Synthesis

General Synthesis of Chiral α,α-Diaryl Carboxamides by Enantioselective Palladium-Catalyzed Cross-Coupling

2020 ◽  
Vol 22 (13) ◽  
pp. 4974-4978
Author(s):  
Bowen Li ◽  
Muinat A. Aliyu ◽  
Zhenhua Gao ◽  
Tiejun Li ◽  
Wei Dong ◽  
...  
Keyword(s):  
Cross Coupling ◽  
Palladium Catalyzed ◽  
General Synthesis

Palladium-Catalyzed Cross Coupling Reactions of β-Iodo-β,γ-enones with Organozinc Chlorides

1997 ◽  
Vol 62 (6) ◽  
pp. 1908-1908
Author(s):  
Fen-Tair Luo ◽  
Li-Chen Hsieh
Keyword(s):  
Cross Coupling ◽  
Coupling Reactions ◽  
Cross Coupling Reactions ◽  
Palladium Catalyzed

Suzuki–Miyaura cross-coupling for chemoproteomic applications

2020 ◽  
Author(s):  
Jian Cao ◽  
Ernest Armenta ◽  
Lisa Boatner ◽  
Heta Desai ◽  
Neil Chan ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Cross Coupling ◽  
Protein Profiling ◽  
Protein Labeling ◽  
Caspase 8 ◽  
Complex Cell ◽  
Bioorthogonal Chemistry ◽  
Reaction Conditions ◽  
Target Deconvolution ◽  
Palladium Catalyzed

Bioorthogonal chemistry is a mainstay of chemoproteomic sample preparation workflows. While numerous transformations are now available, chemoproteomic studies still rely overwhelmingly on copper-catalyzed azide –alkyne cycloaddition (CuAAC) or 'click' chemistry. Here we demonstrate that gel-based activity-based protein profiling (ABPP) and mass-spectrometry-based chemoproteomic profiling can be conducted using Suzuki–Miyaura cross-coupling. We identify reaction conditions that proceed in complex cell lysates and find that Suzuki –Miyaura cross-coupling and CuAAC yield comparable chemoproteomic coverage. Importantly, Suzuki–Miyaura is also compatible with chemoproteomic target deconvolution, as demonstrated using structurally matched probes tailored to react with the cysteine protease caspase-8. Uniquely enabled by the observed orthogonality of palladium-catalyzed cross-coupling and CuAAC, we combine both reactions to achieve dual protein labeling.

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