Palladium-Catalyzed Cross-Coupling between Vinyl Halides andtert-Butyl Carbazate:  First General Synthesis of the UnusualN-Boc-N-alkenylhydrazines

2007 ◽  
Vol 9 (2) ◽  
pp. 275-278 ◽  
Author(s):  
José Barluenga ◽  
Patricia Moriel ◽  
Fernando Aznar ◽  
Carlos Valdés
Keyword(s):  
Cross Coupling ◽  
Vinyl Halides ◽  
Palladium Catalyzed ◽  
General Synthesis

scholarly journals Palladium-Catalyzed Cross-Coupling Between Vinyl Halides and tert-Butyl Carbazate: First General Synthesis of the Unusual N-Boc-N-alkenylhydrazines.

ChemInform ◽  
2007 ◽  
Vol 38 (18) ◽  
Author(s):  
Jose Barluenga ◽  
Patricia Moriel ◽  
Fernando Aznar ◽  
Carlos Valdes
Keyword(s):  
Cross Coupling ◽  
Tert Butyl ◽  
Vinyl Halides ◽  
Palladium Catalyzed ◽  
General Synthesis

Palladium Catalyzed Synthesis of Phenylquinoxaline-Alkyne Derivatives via Sonogashira Cross Coupling Reaction

2021 ◽  
Vol 43 (1) ◽  
pp. 95-95
Author(s):  
Rifhat Bibi Rifhat Bibi ◽  
Muhammad Yaseen Muhammad Yaseen ◽  
Haseen Ahmad Haseen Ahmad ◽  
Ismat Ullah Khan Ismat Ullah Khan ◽  
Shaista Parveen Shaista Parveen ◽  
...  
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Sonogashira Reaction ◽  
Terminal Alkynes ◽  
Vinyl Halides ◽  
Sonogashira Coupling Reaction ◽  
Quinoxaline Derivatives ◽  
Palladium Catalyzed ◽  
High Yields ◽  
Alkyne Derivatives

Transition metals mediated cross coupling methodologies provide an extremely powerful versatile pathway in organic syntheses undoubtedly, a facile route for syntheses and derivatization of biologically important heterocycles from easily available precursors. Sonogashira coupling reaction, a leading method to Csp-Csp2 bond formation is one of the most important and rapid pathways to couple aryl/vinyl halides with terminal alkynes. Current research study deals with the synthesis of alkyne substituted quinoxaline derivatives. The quinoxalines class of aromatic heterocycles exhibits a wide variety of important biological potencies. Palladium catalyzed cross coupling process provided an effective synthetic practice for the synthesis of alkyne derivatives of quinoxaline. Vareity of terminal alkynes were coupled with 2-(4-bromophenyl)quinoxaline under optimized conditions for Sonogashira reaction, affording alkyne substituted quinoxaline derivatives in high yields. The optimized reaction conditions for coupling of range of terminal alkyne with quinoxaline basic core render this process significant for designing of medicinally interesting precursors.

Microwave-Assisted Palladium-Catalyzed Cross-Coupling of Aryl and Vinyl Halides with H-Phosphonate Diesters

2008 ◽  
Vol 10 (20) ◽  
pp. 4637-4640 ◽  
Author(s):  
Marcin Kalek ◽  
Asraa Ziadi ◽  
Jacek Stawinski
Keyword(s):  
Cross Coupling ◽  
Vinyl Halides ◽  
Microwave Assisted ◽  
Palladium Catalyzed

The directed ortho metalation - palladium catalyzed cross coupling connection. A general regiospecific route to 9-phenanthrols and phenanthrenes. Exploratory further metalation

2000 ◽  
Vol 78 (6) ◽  
pp. 905-919 ◽  
Author(s):  
Jian-min Fu ◽  
Victor Snieckus
Keyword(s):  
Cross Coupling ◽  
Ring Contraction ◽  
Ortho Metalation ◽  
Palladium Catalyzed ◽  
General Synthesis

A new general and regiospecific synthesis of 9-phenanthrols (1 +2 [Formula: see text] 3 [Formula: see text] 4, Scheme 1, Table 1) proceeding by a Directed ortho Metalation (DoM), Suzuki-Miyaura cross coupling, and a new LDA-mediated Directed remote Metalation sequence is described. The facile Pd-catalyzed hydrogenolysis of the phenanthrols 4 into the corresponding phenanthrenes 5 via their triflates 18 translates the original DoM regioselectivity also into a general synthesis of phenanthrenes (Table 2). Further DoM (19 [Formula: see text]20, 21; 24 [Formula: see text]25), cross coupling (20c [Formula: see text]23), as well as oxidation - ring contraction (4b, 4f [Formula: see text]28a, 28b) chemistry of phenanthrene derivatives is reported.Key words: 9-phenanthrols, directed ortho metalation, Suzuki cross coupling, synthesis.

ChemInform Abstract: General Synthesis of Retinoids and Arotinoids via Palladium-Catalyzed Cross-Coupling of Boronic Acids with Electrophiles.

ChemInform ◽  
2010 ◽  
Vol 26 (44) ◽  
pp. no-no
Author(s):  
A. TORRADO ◽  
S. LOPEZ ◽  
R. ALVAREZ ◽  
A. R. DE LERA
Keyword(s):  
Cross Coupling ◽  
Boronic Acids ◽  
Palladium Catalyzed ◽  
General Synthesis

General Synthesis of Retinoids and Arotinoids via Palladium-Catalyzed Cross-Coupling of Boronic Acids with Electrophiles

Synthesis ◽  
1995 ◽  
Vol 1995 (03) ◽  
pp. 285-293 ◽  
Author(s):  
Alicia Torrado ◽  
Susana López ◽  
Rosana Alvarez ◽  
Angel R. de Lera
Keyword(s):  
Cross Coupling ◽  
Boronic Acids ◽  
Palladium Catalyzed ◽  
General Synthesis

Highly stereoselective and general synthesis of (z)-3-methyl-2-alken-1-ols via palladium-catalyzed cross coupling of (z)-3-iodo-2-buten-1-ol with organozincs and other organometals

1993 ◽  
Vol 34 (9) ◽  
pp. 1437-1440 ◽  
Author(s):  
Ei-ichi Negishi ◽  
Mehmet Ay ◽  
Yuri V. Gulevich ◽  
Yumiki Noda
Keyword(s):  
Cross Coupling ◽  
Palladium Catalyzed ◽  
General Synthesis
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