ChemInform Abstract: A Short Chemo-Enzymic Route to Glycosphingolipids Using Soluble Glycosyl Transferases.

ChemInform ◽  
2010 ◽  
Vol 25 (36) ◽  
pp. no-no
Author(s):  
B. GUILBERT ◽  
S. L. FLITSCH
1982 ◽  
Vol 104 (1) ◽  
pp. 148-157 ◽  
Author(s):  
M.C. Biol ◽  
A. Martin ◽  
W. Alallon ◽  
P. Louisot ◽  
M. Richard

1996 ◽  
Vol 183 (1) ◽  
pp. 323-327 ◽  
Author(s):  
Q L Yang ◽  
E C Gotschlich

The lipooligosaccharide (LOS) expressed by gonococci spontaneously varies its structure at high frequency, but the underlying genetic mechanism has not been described. We have previously reported that the genes encoding the glycosyl transferases responsible for the biosynthesis of the variable alpha chain of the LOS of Neisseria gonorrhoeae are located in a locus containing five genes, lgtA, lgtB, lgtC, lgtD, and lgtE. Sequence analysis showed that lgtA, lgtC, and lgtD contained poly-G tracts within the coding frames, leading to the hypothesis that shifts in the number of guanosine residues in the poly-G tracts might be responsible for the high frequency variation in structure of gonococcal LOS. We now provide experimental evidence confirming this hypothesis.


1988 ◽  
Vol 34 (5) ◽  
pp. 505-512
Author(s):  
Takayoshi Asai ◽  
Michihiro Itoh ◽  
Hisashi Wakita ◽  
Yoko Nakajima ◽  
Kiyoshi Hiruma ◽  
...  

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