ChemInform Abstract: One-Pot Claisen Rearrangement/O-Methylation/Alkene Isomerization in the Synthesis of ortho-Methoxylated Phenylisopropylamines.

ChemInform ◽  
2010 ◽  
Vol 28 (6) ◽  
pp. no-no
Author(s):  
S. R. WALDMAN ◽  
A. P. MONTE ◽  
A. BRACEY ◽  
D. E. NICHOLS
Keyword(s):  
Claisen Rearrangement ◽  
One Pot ◽  
Alkene Isomerization

One-pot Claisen rearrangement/O-methylation/alkene isomerization in the synthesis of ortho-methoxylated phenylisopropylamines

1996 ◽  
Vol 37 (44) ◽  
pp. 7889-7892 ◽  
Author(s):  
Steve R. Waldman ◽  
Aaron P. Monte ◽  
Ann Bracey ◽  
David E. Nichols
Keyword(s):  
Claisen Rearrangement ◽  
One Pot ◽  
Alkene Isomerization

ChemInform Abstract: Total Synthesis of (-)-Flustramine B via One-Pot Intramolecular Ullmann Coupling and Claisen Rearrangement.

ChemInform ◽  
2009 ◽  
Vol 40 (41) ◽  
Author(s):  
Tomohiro Hirano ◽  
Kanako Iwakiri ◽  
Hiroshi Miyamoto ◽  
Atsuo Nakazaki ◽  
Susumu Kobayashi
Keyword(s):  
Total Synthesis ◽  
Claisen Rearrangement ◽  
One Pot ◽  
Ullmann Coupling

scholarly journals Zinc Chloride Catalyzed Amino Claisen Rearrangement of 1-N-Allylindolines: An Expedient Protocol for the Synthesis of Functionalized 7-Allylindolines

2019 ◽  
Vol 25 (1) ◽  
pp. 22-26 ◽  
Author(s):  
Seema Jain
Keyword(s):  
Zinc Chloride ◽  
Claisen Rearrangement ◽  
Reaction System ◽  
Biologically Active ◽  
Catalyst Loading ◽  
One Pot ◽  
Substitution Pattern ◽  
Claisen Rearrangements ◽  
Lower Temperature ◽  
Molecular Libraries

Abstract7-Allylindolines are valuable synthons for designing biologically active molecular libraries. Lewis acid catalyzed amino-Claisen rearrangement provides a one pot synthetic entry to these heteroarenes. In this context, Zinc chloride (ZnCl2)–N,N-dimethylformamide system efficiently catalyzed amino-Claisen rearrangements of 1-N-allylindolines to 7-allylindolines. The rearrangement is influenced by stereoelectronic effects of substituents present in 1-N-allylindolines. The substrates containing electron donating functionalities underwent rearrangement at lower temperature than substrates with electron withdrawing functional groups. The regioselectivity of the process is governed by the substitution pattern on allyl moiety in 1-N-allylindoline as well as ZnCl2 catalyst loading in the reaction system.

Stereoselective three-component cascade synthesis of α-substituted 2,4-dienamides from gem-difluorochloro ethanes

2019 ◽  
Vol 55 (95) ◽  
pp. 14355-14358
Author(s):  
Shyamsundar Das ◽  
Nakeun Ko ◽  
Eunsung Lee ◽  
Sang Eun Kim ◽  
Byung Chul Lee
Keyword(s):  
Transition Metal ◽  
Claisen Rearrangement ◽  
Cascade Reaction ◽  
One Pot ◽  
Metal Free

Herein, we describe a new transition metal-free Claisen rearrangement for the synthesis of α-substituted 2,4-dienamide. This one-pot, stereoselective three-component cascade reaction affords various polysubstituted 2,4-dienamides in good yields.

scholarly journals Synthesis of Alkylidene(gem-Difluorocyclopropanes) from Propargyl Glycolates by a One-Pot Difluorocyclopropenation/Ireland–Claisen Rearrangement Sequence

2017 ◽  
Vol 82 (7) ◽  
pp. 3965-3975 ◽  
Author(s):  
Guillaume Ernouf ◽  
Jean-Louis Brayer ◽  
Benoît Folléas ◽  
Jean-Pierre Demoute ◽  
Christophe Meyer ◽  
...  
Keyword(s):  
Claisen Rearrangement ◽  
One Pot
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