ChemInform Abstract: Biochemical Studies on Natural Products. Part 5. Enantioselective Synthesis of (S)- and (R)-Mappicines and Their Analogues.

ChemInform ◽  
2010 ◽  
Vol 30 (37) ◽  
pp. no-no
Author(s):  
Biswanath Das ◽  
P. Madhusudhan
Keyword(s):  
Natural Products ◽  
Enantioselective Synthesis ◽  
Biochemical Studies

Enantioselective Syntheses of Flavonoid Diels-Alder Natural Products: A Review

2018 ◽  
Vol 15 (2) ◽  
pp. 221-229 ◽  
Author(s):  
Shah Bakhtiar Nasir ◽  
Noorsaadah Abd Rahman ◽  
Chin Fei Chee
Keyword(s):  
Natural Products ◽  
Organic Synthesis ◽  
Lewis Acid ◽  
Alder Reaction ◽  
Diels Alder ◽  
Enantioselective Synthesis ◽  
Chiral Ligand ◽  
Asymmetric Syntheses ◽  
Diels Alder Reaction ◽  
Enantioselective Syntheses

Background: The Diels-Alder reaction has been widely utilised in the syntheses of biologically important natural products over the years and continues to greatly impact modern synthetic methodology. Recent discovery of chiral organocatalysts, auxiliaries and ligands in organic synthesis has paved the way for their application in Diels-Alder chemistry with the goal to improve efficiency as well as stereochemistry. Objective: The review focuses on asymmetric syntheses of flavonoid Diels-Alder natural products that utilize chiral ligand-Lewis acid complexes through various illustrative examples. Conclusion: It is clear from the review that a significant amount of research has been done investigating various types of catalysts and chiral ligand-Lewis acid complexes for the enantioselective synthesis of flavonoid Diels-Alder natural products. The results have demonstrated improved yield and enantioselectivity. Much emphasis has been placed on the synthesis but important mechanistic work aimed at understanding the enantioselectivity has also been discussed.

Enantioselective synthesis of pyrro[3,4-c]quinoline pseudo-natural products

2021 ◽  
pp. 153228
Author(s):  
Jie Liu ◽  
Felix Otte ◽  
Carsten Strohmann ◽  
Herbert Waldmann
Keyword(s):  
Natural Products ◽  
Enantioselective Synthesis

scholarly journals Molecular and Biochemical Studies of Chondramide Formation—Highly Cytotoxic Natural Products from Chondromyces crocatus Cm c5

2006 ◽  
Vol 13 (6) ◽  
pp. 667-681 ◽  
Author(s):  
Shwan Rachid ◽  
Daniel Krug ◽  
Brigitte Kunze ◽  
Irene Kochems ◽  
Maren Scharfe ◽  
...  
Keyword(s):  
Natural Products ◽  
Biochemical Studies

scholarly journals Development of a Divergent Route to Erythrina Alkaloids

Synlett ◽  
2020 ◽  
Vol 31 (04) ◽  
pp. 327-333 ◽  
Author(s):  
Jesper L. Kristensen ◽  
Sebastian Clementson ◽  
Mikkel Jessing ◽  
Paulo J. Vital
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
19Th Century ◽  
First Generation ◽  
Second Generation ◽  
Enantioselective Synthesis ◽  
Third Generation ◽  
Synthetic Strategy ◽  
Erythrina Alkaloids ◽  
The 19Th Century

Erythrina alkaloids were identified at the end of the 19th century and today, more than 100 members of the erythrinane family have been isolated. They are characterized by a unique tetracyclic, α-tertiary spiroamine scaffold. Herein we detail our efforts towards the development of a divergent enantioselective synthesis of (+)-dihydro-β-erythroidine (DHβE) – one of the most prominent members of this intriguing family of natural products.1 Introduction2 Synthetic Strategy2.1 First Generation2.2 Second Generation2.3 Third Generation2.3.1 Radical Endgame2.3.2 Completion of the Total Synthesis3 Conclusion

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