ChemInform Abstract: Treatment of N-Boc Derivatives of β-amino Alcohols with N,N-Diethylaminosulfur Trifluoride Leads to Chiral Oxazolidinones: An Unexpected Intramolecular Cyclization.

ChemInform ◽  
2010 ◽  
Vol 30 (50) ◽  
pp. no-no
Author(s):  
He Zhao ◽  
Andrew Thurkauf
1996 ◽  
Vol 61 (2) ◽  
pp. 288-297 ◽  
Author(s):  
Vladimír Pouzar ◽  
Ivan Černý

New approach to the preparation of steroids with connecting bridge, based on an O-carboxymethyloxime (CMO) structure, and with terminal hydroxy group, is presented. 17-CMO derivatives of 3β-acetoxy- and 3β-methoxymethoxyandrost-5-en-17-one were condensed with α,ω-amino alcohols to give derivatives with a chain of seven to nine atoms. After THP-protection, these compounds were converted to 3-keto-4-ene derivatives. An alternative synthesis consisted in transformation of 17-CMO derivatives with bonded amino acids by reduction of the terminal carboxyl. The resulting compounds were designed as building blocks for the preparation of bis-haptens for sandwich immunoassays.


ChemInform ◽  
2010 ◽  
Vol 24 (34) ◽  
pp. no-no
Author(s):  
S. V. AMOSOVA ◽  
N. I. IVANOVA ◽  
G. A. KALABIN ◽  
S. V. ZINCHENKO ◽  
M. V. SIGALOV

1938 ◽  
Vol 60 (6) ◽  
pp. 1321-1325 ◽  
Author(s):  
Jacob van de Kamp ◽  
Alfred Burger ◽  
Erich Mosettig

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