Design, Synthesis and Biological Activity of Rigid Cannabinoid CB1 Receptor Antagonists.

Receptor Antagonists ◽

Design Synthesis ◽

Design, Synthesis and Biological Activity of Rigid Cannabinoid CB1 Receptor Antagonists

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.50.1109 ◽

2002 ◽

Vol 50 (8) ◽

pp. 1109-1113 ◽

Cited By ~ 47

Author(s):

Axel Reinhard Stoit ◽

Jos Hubertus Maria Lange ◽

Arnold Peter den Hartog ◽

Eric Ronken ◽

Koos Tipker ◽

...

Keyword(s):

Biological Activity ◽

Cb1 Receptor ◽

Receptor Antagonists ◽

Design Synthesis ◽

Cannabinoid Cb1 Receptor Antagonists/Inverse Agonists and Food-Seeking Behavior

Handbook of Behavior, Food and Nutrition ◽

10.1007/978-0-387-92271-3_29 ◽

2011 ◽

pp. 441-456

Author(s):

John D. Salamone ◽

Kelly Sink ◽

Kristen N. Segovia ◽

Patrick A. Randall ◽

Peter J. McLaughlin ◽

...

Keyword(s):

Cb1 Receptor ◽

Receptor Antagonists ◽

Inverse Agonists ◽

Seeking Behavior ◽

Food Seeking ◽

Potential antipsychotic properties of central cannabinoid (CB1) receptor antagonists

The World Journal of Biological Psychiatry ◽

10.1080/15622970801908047 ◽

2008 ◽

pp. 1-12 ◽

Cited By ~ 4

Author(s):

Patrik Roser ◽

Franz Vollenweider ◽

Wolfram Kawohl

Keyword(s):

Cb1 Receptor ◽

Receptor Antagonists ◽

The cannabinoid CB1 receptor antagonists rimonabant (SR141716) and AM251 directly potentiate GABAA receptors

British Journal of Pharmacology ◽

10.1111/j.1476-5381.2011.01405.x ◽

2012 ◽

Vol 165 (8) ◽

pp. 2479-2484 ◽

Cited By ~ 24

Author(s):

R Baur ◽

J Gertsch ◽

E Sigel

Keyword(s):

Gabaa Receptors ◽

Cb1 Receptor ◽

Receptor Antagonists ◽

Synthesis and SAR of 1,4,5,6-tetrahydropyridazines as potent cannabinoid CB1 receptor antagonists

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2009.08.007 ◽

2009 ◽

Vol 19 (19) ◽

pp. 5675-5678 ◽

Cited By ~ 16

Author(s):

Jos H.M. Lange ◽

Arnold P. den Hartog ◽

Martina A.W. van der Neut ◽

Bernard J. van Vliet ◽

Chris G. Kruse

Keyword(s):

Cb1 Receptor ◽

Receptor Antagonists ◽

Cannabinoid CB1 receptor antagonists

Drug Development Research ◽

10.1002/ddr.20361 ◽

2010 ◽

pp. n/a-n/a

Keyword(s):

Cb1 Receptor ◽

Receptor Antagonists ◽

A therapeutic role for cannabinoid CB1 receptor antagonists in major depressive disorders

Trends in Pharmacological Sciences ◽

10.1016/j.tips.2005.10.006 ◽

2005 ◽

Vol 26 (12) ◽

pp. 609-617 ◽

Cited By ~ 67

Author(s):

Jeffrey M. Witkin ◽

Eleni T. Tzavara ◽

Richard J. Davis ◽

Xia Li ◽

George G. Nomikos

Keyword(s):

Depressive Disorders ◽

Cb1 Receptor ◽

Receptor Antagonists ◽

Major Depressive ◽

Therapeutic Role ◽

Major Depressive Disorders ◽

Identification of Novel Cannabinoid CB1 Receptor Antagonists by Using Virtual Screening with a Pharmacophore Model

Journal of Medicinal Chemistry ◽

10.1021/jm701519h ◽

2008 ◽

Vol 51 (8) ◽

pp. 2439-2446 ◽

Cited By ~ 37

Author(s):

Hongwu Wang ◽

Ruth A. Duffy ◽

George C. Boykow ◽

Samuel Chackalamannil ◽

Vincent S. Madison

Keyword(s):

Virtual Screening ◽

Pharmacophore Model ◽

Cb1 Receptor ◽

Receptor Antagonists ◽

Cannabinoid CB1 receptor antagonists as potential pharmacotherapies for drug abuse disorders

International Review of Psychiatry ◽

10.1080/09540260902782786 ◽

2009 ◽

Vol 21 (2) ◽

pp. 134-142 ◽

Cited By ~ 23

Author(s):

Patrick M. Beardsley ◽

Brian F. Thomas ◽

Lance R. Mcmahon

Keyword(s):

Drug Abuse ◽

Cb1 Receptor ◽

Receptor Antagonists ◽

Synthesis and Docking of new (2-(2,5-dimethoxyphenyl)-1Hbenzo[ d]imidazol-1-yl)(aryl)methanone derivatives designed as novel cannabinoid CB1 receptor antagonists.

10.5151/chempro-14bmos-r0169-1 ◽

2013 ◽

Author(s):

C Espinosa-Bustos ◽

C. F. Lagos ◽

J. Romero-Parra ◽

J. Mella-Raipán ◽

H. Pessoa- Mahana ◽

...

Keyword(s):

Cb1 Receptor ◽

Receptor Antagonists ◽