Palladium Catalyzed Double Substitution Reactions of Iodophenol and Iodoaniline Derivatives with Homo-Conjugated Compounds to Form Cyclic Ether and Cyclic Amines Through Homo-Conjugated Interaction

ChemInform ◽  
2003 ◽  
Vol 34 (3) ◽  
Author(s):  
Katsuhiro Saito ◽  
Katsuhiko Ono ◽  
Makiko Sano ◽  
Shingo Kiso ◽  
Toshihumi Takeda
Keyword(s):  
Cyclic Ether ◽  
Substitution Reactions ◽  
Cyclic Amines ◽  
Palladium Catalyzed ◽  
Double Substitution ◽  
Conjugated Compounds

ChemInform Abstract: Palladium-Catalyzed Substitution Reactions of geminal Allylic Diacetates.

ChemInform ◽  
2010 ◽  
Vol 29 (41) ◽  
pp. no-no
Author(s):  
F. R. VAN HEERDEN ◽  
J. J. HUYSER ◽  
D. B. G. WILLIAMS ◽  
C. W. HOLZAPFEL
Keyword(s):  
Substitution Reactions ◽  
Palladium Catalyzed

Chiral P,Olefin Ligands with Rotamers for Palladium-Catalyzed Asymmetric Allylic Substitution Reactions

Synlett ◽  
2020 ◽  
Author(s):  
Takashi Mino ◽  
Daiki Yamaguchi ◽  
Manami Kumada ◽  
Junpei Youda ◽  
Hironori Saito ◽  
...  
Keyword(s):  
Chiral Ligands ◽  
Allylic Substitution ◽  
Substitution Reactions ◽  
Palladium Catalyzed

We synthesized a series of phosphine–olefin-type chiral aminophosphines, and we confirmed that these each exists as two rotamers at the C(aryl)–N(amine) bond. We also investigated the ability of these aminophosphines to act as chiral ligands for Pd-catalyzed asymmetric allylic substitution reactions, such as the alkylation of allylic acetates with malonates or indoles, and we found they gave high enantio­selectivities (up to 98% ee).

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