ChemInform Abstract: I2/CuO-Catalyzed Tandem Cyclization Strategy for One-Pot Synthesis of Substituted 2-Aminothiazole from Easily Available Aromatic Ketones/α,β-Unsaturated Ketones and Thiourea.
Herein we report a sequential one-pot alkyne dimerization/hydration protocol for the regioselective synthesis of α,β-unsaturated ketones in quantitive yields. The alkyne dimerization reactions of terminal arylacetylenes proceeded with high regioselectivity...