One-pot Synthesis of α,β-Unsaturated Ketones through Sequential Alkyne Dimerization/Hydration Reactions using Hoveyda-Grubbs Catalyst

2021 ◽  
Author(s):  
Bengi Öztürk ◽  
Begüm Sarıaslan ◽  
Mina Aşkun ◽  
Zeynep Tunalı ◽  
Solmaz Karabulut
Keyword(s):  
Regioselective Synthesis ◽  
Grubbs Catalyst ◽  
One Pot ◽  
Unsaturated Ketones ◽  
One Pot Synthesis

Herein we report a sequential one-pot alkyne dimerization/hydration protocol for the regioselective synthesis of α,β-unsaturated ketones in quantitive yields. The alkyne dimerization reactions of terminal arylacetylenes proceeded with high regioselectivity...

A “one pot” synthesis of polysubstituted pyridines from metallated alkylphosphonates, nitriles and α,β-unsaturated ketones

1996 ◽  
Vol 37 (26) ◽  
pp. 4577-4580 ◽  
Author(s):  
Francisco Palacios ◽  
Ana M. Ochoa de Retana ◽  
Julen Oyarzabal
Keyword(s):  
One Pot ◽  
Unsaturated Ketones ◽  
One Pot Synthesis

One-pot synthesis of α,β-unsaturated ketones from tert-butyldimethylsilyldibromomethane and two different aldehydes

1994 ◽  
Vol 35 (22) ◽  
pp. 3741-3744 ◽  
Author(s):  
Hiroshi Shinokubo ◽  
Koichiro Oshima ◽  
Kiitiro Utimoto
Keyword(s):  
One Pot ◽  
Unsaturated Ketones ◽  
One Pot Synthesis

Reaction of isatins with 6-amino uracils and isoxazoles: isatin ring-opening vs. annulations and regioselective synthesis of isoxazole fused quinoline scaffolds in water

2015 ◽  
Vol 17 (6) ◽  
pp. 3362-3372 ◽  
Author(s):  
Nataraj Poomathi ◽  
Sivakalai Mayakrishnan ◽  
Doraiswamy Muralidharan ◽  
Rajagopal Srinivasan ◽  
Paramasivan T. Perumal
Keyword(s):  
Ring Opening ◽  
Sulphonic Acid ◽  
Regioselective Synthesis ◽  
One Pot ◽  
One Pot Synthesis ◽  
The One ◽  
Straightforward Approach

A straightforward approach for the one-pot synthesis of isoxazoloquinoline and spiroxindole derivatives in water has been established using p-toluene sulphonic acid as a catalyst.

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