ChemInform Abstract: Chemical Synthesis of the Cardiotonic Steroid Glycosides and Related Natural Products.

ChemInform ◽  
2012 ◽  
Vol 43 (29) ◽  
pp. no-no
Author(s):  
Brian Heasley
2006 ◽  
pp. 51-89 ◽  
Author(s):  
Steven V. Ley ◽  
Ian R. Baxendale ◽  
Deborah A. Longbottom ◽  
Rebecca M. Myers

Author(s):  
Rishab N. Iyer ◽  
David Favela ◽  
Guoliang Zhang ◽  
David E. Olson

Few classes of natural products have inspired as many chemists and biologists as have the iboga alkaloids. This review covers recent advances in the biosynthesis and chemical synthesis of iboga alkaloids and their use as neurotherapeutics.


1993 ◽  
Vol 39 (2) ◽  
pp. 131-140 ◽  
Author(s):  
John B. Pillmoor ◽  
Kenneth Wright ◽  
Adrian S. Terry

ChemInform ◽  
2013 ◽  
Vol 44 (19) ◽  
pp. no-no
Author(s):  
Dana K. Winter ◽  
David L. Sloman ◽  
Jr. Porco John A

Author(s):  
Arthur Han ◽  
Yujia Tao ◽  
Sarah Reisman

(+)-Perseanol is an isoryanodane diterpene with potent antifeedant and insecticidal properties isolated from the tropical shrub <i>Persea indica</i>. Here we report the first chemical synthesis of (+)-perseanol, which proceeds in 16 steps from commercially available (<i>R</i>)-pulegone. The synthesis features a two-step annulation process that rapidly assembles the tetracyclic core from readily accessible cyclopentyl building blocks. This work demonstrates how convergent fragment coupling, when combined with strategic oxidation tactics, can enable the concise synthesis of complex and highly oxidized diterpene natural products. <br>


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