Discovery of Heterocyclic Nonacetamide Synaptic Vesicle Protein 2A (SV2A) Ligands with Single-Digit Nanomolar Potency: Opening Avenues towards the First SV2A Positron Emission Tomography (PET) Ligands

ChemMedChem ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. 693-698 ◽  
Author(s):  
Joël Mercier ◽  
Laurence Archen ◽  
Véronique Bollu ◽  
Stéphane Carré ◽  
Yves Evrard ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Synaptic Vesicle ◽  
Emission Tomography ◽  
Single Digit ◽  
Synaptic Vesicle Protein ◽  
Positron Emission ◽  
Vesicle Protein ◽  
Synaptic Vesicle Protein 2A

Preferential increase in the hippocampal synaptic vesicle protein 2A (SV2A) by pentylenetetrazole kindling

2009 ◽  
Vol 390 (3) ◽  
pp. 415-420 ◽  
Author(s):  
Yukihiro Ohno ◽  
Shizuka Ishihara ◽  
Ryo Terada ◽  
Miki Kikuta ◽  
Nobumasa Sofue ◽  
...  
Keyword(s):  
Synaptic Vesicle ◽  
Synaptic Vesicle Protein ◽  
Vesicle Protein ◽  
Synaptic Vesicle Protein 2A

scholarly journals Synaptic vesicle protein 2A as a potential biomarker in synaptopathies

2019 ◽  
Vol 97 ◽  
pp. 34-42 ◽  
Author(s):  
Kerstin Heurling ◽  
Nicholas J. Ashton ◽  
Antoine Leuzy ◽  
Eduardo R. Zimmer ◽  
Kaj Blennow ◽  
...  
Keyword(s):  
Synaptic Vesicle ◽  
Synaptic Vesicle Protein ◽  
Potential Biomarker ◽  
Vesicle Protein ◽  
Synaptic Vesicle Protein 2A

scholarly journals Function of synaptic vesicle protein 2A (SV2A) as a novel therapeutic target for epilepsy

2018 ◽  
Vol 152 (6) ◽  
pp. 275-280
Author(s):  
Kentaro Tokudome ◽  
Saki Shimizu ◽  
Tadao Serikawa ◽  
Yukihiro Ohno
Keyword(s):  
Synaptic Vesicle ◽  
Therapeutic Target ◽  
Synaptic Vesicle Protein ◽  
Vesicle Protein ◽  
Synaptic Vesicle Protein 2A ◽  
Novel Therapeutic

scholarly journals Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

1999 ◽  
Vol 96 (26) ◽  
pp. 15268-15273 ◽  
Author(s):  
K. M. Crowder ◽  
J. M. Gunther ◽  
T. A. Jones ◽  
B. D. Hale ◽  
H. Z. Zhang ◽  
...  
Keyword(s):  
Synaptic Vesicle ◽  
Synaptic Vesicle Protein ◽  
Vesicle Protein ◽  
Synaptic Vesicle Protein 2A

Interaction of Approved Drugs with Synaptic Vesicle Protein 2A

2017 ◽  
Vol 350 (3-4) ◽  
pp. 1700003 ◽  
Author(s):  
Azeem Danish ◽  
Vigneshwaran Namasivayam ◽  
Anke C. Schiedel ◽  
Christa E. Müller
Keyword(s):  
Synaptic Vesicle ◽  
Synaptic Vesicle Protein ◽  
Vesicle Protein ◽  
Approved Drugs ◽  
Synaptic Vesicle Protein 2A

scholarly journals Evaluation of 18F-UCB-H as a Novel PET Tracer for Synaptic Vesicle Protein 2A in the Brain

2014 ◽  
Vol 55 (8) ◽  
pp. 1336-1341 ◽  
Author(s):  
G. I. Warnock ◽  
J. Aerts ◽  
M. A. Bahri ◽  
F. Bretin ◽  
C. Lemaire ◽  
...  
Keyword(s):  
Synaptic Vesicle ◽  
Synaptic Vesicle Protein ◽  
Pet Tracer ◽  
Vesicle Protein ◽  
Synaptic Vesicle Protein 2A ◽  
The Brain

Expression patterns of synaptic vesicle protein 2A in focal cortical dysplasia and TSC-cortical tubers

Epilepsia ◽  
2009 ◽  
Vol 50 (6) ◽  
pp. 1409-1418 ◽  
Author(s):  
Sjoukje T. Toering ◽  
Karin Boer ◽  
Marjolein de Groot ◽  
Dirk Troost ◽  
Jan J. Heimans ◽  
...  
Keyword(s):  
Synaptic Vesicle ◽  
Focal Cortical Dysplasia ◽  
Expression Patterns ◽  
Cortical Dysplasia ◽  
Synaptic Vesicle Protein ◽  
Cortical Tubers ◽  
Vesicle Protein ◽  
Synaptic Vesicle Protein 2A
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