scholarly journals Biological Characterization, Mechanistic Investigation and Structure‐Activity Relationships of Chemically Stable TLR2 Antagonists

ChemMedChem ◽  
2020 ◽  
Vol 15 (14) ◽  
pp. 1364-1371 ◽  
Author(s):  
Marcel Bermudez ◽  
Maria Grabowski ◽  
Manuela S. Murgueitio ◽  
Markus Tiemann ◽  
Péter Varga ◽  
...  
Keyword(s):  
Biological Characterization ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Mechanistic Investigation

Structure–Activity Relationships and Biological Characterization of a Novel, Potent, and Serum Stable C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonist

2017 ◽  
Vol 60 (23) ◽  
pp. 9641-9652 ◽  
Author(s):  
Salvatore Di Maro ◽  
Francesco Saverio Di Leva ◽  
Anna Maria Trotta ◽  
Diego Brancaccio ◽  
Luigi Portella ◽  
...  
Keyword(s):  
Chemokine Receptor ◽  
Receptor Type ◽  
Biological Characterization ◽  
Cxcr4 Antagonist ◽  
Structure Activity Relationships ◽  
Structure Activity

scholarly journals Phytotoxic Terpenes Produced by Phytopathogenic Fungi and Allelopathic Plants

2014 ◽  
Vol 9 (3) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Alessio Cimmino ◽  
Anna Andolfi ◽  
Antonio Evidente
Keyword(s):  
Mode Of Action ◽  
Potential Application ◽  
Fungal Pathogens ◽  
Phytopathogenic Fungi ◽  
Biological Characterization ◽  
Anticancer Compounds ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Forest Plants

This review is about the isolation as well as chemical and biological characterization of simple and complex mono-, sesqui-, di-, sester- and tri-terpenes produced by fungal pathogens of agrarian and forest plants and by some allelopathic plants. In several cases, the structure activity relationships are also discussed, as well as their potential application in agriculture as natural safe herbicides, fungicides and bactericides. Furthermore, the potential application of some fungal terpenes as anticancer compounds with a new mode of action is also discussed.

scholarly journals Ruthenium complexes endowed with potent anti-Trypanosoma cruzi activity: Synthesis, biological characterization and structure–activity relationships

2009 ◽  
Vol 17 (14) ◽  
pp. 5038-5043 ◽  
Author(s):  
Claudio Luis Donnici ◽  
Maria Helena Araújo ◽  
Henrique S. Oliveira ◽  
Diogo Rodrigo Magalhães Moreira ◽  
Valéria R. Alves Pereira ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Ruthenium Complexes ◽  
Biological Characterization ◽  
Structure Activity Relationships ◽  
Structure Activity
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