Multi‐institutional, randomized, double‐blind, placebo‐controlled trial to assess the efficacy of a mucoadhesive hydrogel (MuGard) in mitigating oral mucositis symptoms in patients being treated with chemoradiation therapy for cancers of the head and neck

Ron R. Allison; Aaron A. Ambrad; Youssef Arshoun; Richard J. Carmel; Doug F. Ciuba; Elizabeth Feldman; Steven E. Finkelstein; Ranjini Gandhavadi; Dwight E. Heron; Steven C. Lane; John M. Longo; Charles Meakin; Dimitrios Papadopoulos; David E. Pruitt; Lynn M. Steinbrenner; Michael A. Taylor; William M. Wisbeck; Grace E. Yuh; David P. Nowotnik; Stephen T. Sonis

doi:10.1002/cncr.28553

Multi‐institutional, randomized, double‐blind, placebo‐controlled trial to assess the efficacy of a mucoadhesive hydrogel (MuGard) in mitigating oral mucositis symptoms in patients being treated with chemoradiation therapy for cancers of the head and neck

Cancer ◽

10.1002/cncr.28553 ◽

2014 ◽

Vol 120 (9) ◽

pp. 1433-1440 ◽

Cited By ~ 35

Author(s):

Ron R. Allison ◽

Aaron A. Ambrad ◽

Youssef Arshoun ◽

Richard J. Carmel ◽

Doug F. Ciuba ◽

...

Keyword(s):

Head And Neck ◽

Oral Mucositis ◽

Controlled Trial ◽

Chemoradiation Therapy ◽

Double Blind ◽

Double Blind Placebo

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Results from the Multi-institutional, Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Efficacy of a Mucoadhesive Hydrogel Rinse in Mitigating Oral Mucositis (OM) in Chemoradiation-Treated (CRT) Head-and-Neck Cancer (HNC) Patients

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2013.06.1514 ◽

2013 ◽

Vol 87 (2) ◽

pp. S571

Author(s):

D.P. Nowotnik ◽

R.R. Allison ◽

Y.M. Arshoun ◽

R. Carmel ◽

D.F. Ciuba ◽

...

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Neck Cancer ◽

Oral Mucositis ◽

Controlled Trial ◽

Double Blind ◽

Double Blind Placebo

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Randomized double-blind placebo-controlled trial of celecoxib for oral mucositis in patients receiving radiation therapy for head and neck cancer

Oral Oncology ◽

10.1016/j.oraloncology.2014.08.001 ◽

2014 ◽

Vol 50 (11) ◽

pp. 1098-1103 ◽

Cited By ~ 19

Author(s):

Rajesh V. Lalla ◽

Linda E. Choquette ◽

Kathleen F. Curley ◽

Robert J. Dowsett ◽

Richard S. Feinn ◽

...

Keyword(s):

Radiation Therapy ◽

Head And Neck Cancer ◽

Head And Neck ◽

Neck Cancer ◽

Oral Mucositis ◽

Controlled Trial ◽

Double Blind ◽

Double Blind Placebo

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Randomized, Double-Blind, Placebo-Controlled Trial of Shuanghua Baihe Tablets to Prevent Oral Mucositis in Patients With Nasopharyngeal Cancer Undergoing Chemoradiation Therapy

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2017.10.013 ◽

2018 ◽

Vol 100 (2) ◽

pp. 418-426 ◽

Cited By ~ 5

Author(s):

Baomin Zheng ◽

Xiaodong Zhu ◽

Mengzhong Liu ◽

Zhenzhou Yang ◽

Ling Yang ◽

...

Keyword(s):

Oral Mucositis ◽

Controlled Trial ◽

Nasopharyngeal Cancer ◽

Chemoradiation Therapy ◽

Double Blind ◽

Double Blind Placebo

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Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: results from the DAHANCA 5 randomised double-blind placebo-controlled trial

The Lancet Oncology ◽

10.1016/s1470-2045(05)70292-8 ◽

2005 ◽

Vol 6 (10) ◽

pp. 757-764 ◽

Cited By ~ 203

Author(s):

Jens Overgaard ◽

Jesper Grau Eriksen ◽

Marianne Nordsmark ◽

Jan Alsner ◽

Michael R Horsman

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Neck Cancer ◽

Controlled Trial ◽

Double Blind ◽

Double Blind Placebo

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Ketamine Mouthwash versus Placebo in the Treatment of Severe Oral Mucositis Pain in Children with Cancer: A Randomized Double-Blind Placebo-Controlled Trial

10.22541/au.159136808.85363464 ◽

2020 ◽

Author(s):

Satya Prakash ◽

Jagdish Meena ◽

Aditya Gupta ◽

Sameer Bakhshi ◽

Thirumurthy Velpandian ◽

...

Keyword(s):

Oral Mucositis ◽

Controlled Trial ◽

Children With Cancer ◽

Double Blind ◽

Double Blind Placebo ◽

Severe Oral Mucositis

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Can acetylcysteine ameliorate cisplatin‐induced toxicities and oxidative stress without decreasing antitumor efficacy? A randomized, double‐blind, placebo‐controlled trial involving patients with head and neck cancer

Cancer Medicine ◽

10.1002/cam4.2072 ◽

2019 ◽

Vol 8 (5) ◽

pp. 2020-2030 ◽

Cited By ~ 6

Author(s):

Marília B. Visacri ◽

Júlia C. F. Quintanilha ◽

Vanessa M. Sousa ◽

Laís S. Amaral ◽

Rosiane Ambrósio ◽

...

Keyword(s):

Oxidative Stress ◽

Head And Neck Cancer ◽

Head And Neck ◽

Neck Cancer ◽

Controlled Trial ◽

Antitumor Efficacy ◽

Double Blind ◽

Double Blind Placebo ◽

And Oxidative Stress

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Effects of fluconazole in the prophylaxis of oropharyngeal candidiasis in patients undergoing radiotherapy for head and neck tumour: results from a double-blind placebo-controlled trial

European Journal of Cancer Care ◽

10.1111/j.1365-2354.2007.00855.x ◽

2008 ◽

Vol 17 (3) ◽

pp. 270-277 ◽

Cited By ~ 14

Author(s):

R. CORVÒ ◽

M. AMICHETTI ◽

A. ASCARELLI ◽

G. ARCANGELI ◽

A. BUFFOLI ◽

...

Keyword(s):

Head And Neck ◽

Controlled Trial ◽

Oropharyngeal Candidiasis ◽

Double Blind ◽

Double Blind Placebo ◽

Neck Tumour

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A double-blind, randomized, placebo-controlled trial of l-glutamine for the severe oral mucositis induced by chemoradiotherapy in patients with locally advanced head and neck cancer.

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.15_suppl.6059 ◽

2014 ◽

Vol 32 (15_suppl) ◽

pp. 6059-6059

Author(s):

Takae Tsujimoto ◽

Yoshifumi Yamamoto ◽

Masafumi Wasa ◽

Yukinori Takenaka ◽

Wataru Nakahara ◽

...

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Neck Cancer ◽

Oral Mucositis ◽

Controlled Trial ◽

Locally Advanced ◽

Advanced Head ◽

Double Blind ◽

Severe Oral Mucositis

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Efficacy and safety of rebamipide liquid for chemoradiotherapy-induced oral mucositis in patients with head and neck cancer: a multicenter, randomized, double-blind, placebo-controlled, parallel-group phase II study

BMC Cancer ◽

10.1186/s12885-017-3295-4 ◽

2017 ◽

Vol 17 (1) ◽

Cited By ~ 14

Author(s):

T. Yokota ◽

T. Ogawa ◽

S. Takahashi ◽

K. Okami ◽

T. Fujii ◽

...

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Phase Ii ◽

Neck Cancer ◽

Oral Mucositis ◽

Phase Ii Study ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group

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340 poster A randomized, double-blind, placebo-controlled trial of concomitant pilocarpine with head and neck irradiation for prevention of radiation-induced xerostomia

Radiotherapy and Oncology ◽

10.1016/s0167-8140(01)80480-1 ◽

2001 ◽

Vol 58 ◽

pp. S91-S92

Keyword(s):

Head And Neck ◽

Controlled Trial ◽

Double Blind ◽

Double Blind Placebo ◽

Neck Irradiation ◽

Radiation Induced ◽

Head And Neck Irradiation

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