Review of drug development and therapeutic role of cholinesterase inhibitors in Alzheimer's disease

2002 ◽  
Vol 56 (3) ◽  
pp. 347-353 ◽  
Author(s):  
John J. Sramek ◽  
Victoria Zarotsky ◽  
Neal R. Cutler
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Drug Development ◽  
Cholinesterase Inhibitors ◽  
Therapeutic Role

Therapeutic role of MSCs-derived exosomes for Alzheimer's disease.

2020 ◽  
Vol 37 (2) ◽  
pp. 1-12
Author(s):  
Sara M. Kamal ◽  
Aliaa R.H. Mostafa ◽  
Sanaa M.R. Wahba
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Therapeutic Role

An overview of the possible therapeutic role of SUMOylation in the treatment of Alzheimer’s disease

2018 ◽  
Vol 130 ◽  
pp. 420-437 ◽  
Author(s):  
S. Marcelli ◽  
E. Ficulle ◽  
L. Piccolo ◽  
M. Corbo ◽  
M. Feligioni
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Therapeutic Role

Carotenoids and Alzheimer’s Disease: An insight into therapeutic role of retinoids in animal models

2011 ◽  
Vol 59 (5) ◽  
pp. 535-541 ◽  
Author(s):  
M. Obulesu ◽  
Muralidhara Rao Dowlathabad ◽  
P.V. Bramhachari
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Animal Models ◽  
Therapeutic Role ◽  
Insight Into

scholarly journals ROLE OF THE HYPOTHALAMIC-PITUITARY-GONADAL SYSTEM IN THE PATHOGENESIS OF ALZHEIMER’S DISEASE

2018 ◽  
Vol 18 (1) ◽  
pp. 16-26
Author(s):  
O O Masalova ◽  
S B Kazakova ◽  
N S Sapronov
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Sex Steroids ◽  
Cholinesterase Inhibitors ◽  
Significant Contribution ◽  
Nmda Antagonists ◽  
Degenerative Diseases ◽  
Promising Area ◽  
Serious Disease

Alzheimer's disease (AD) is the most common from degenerative diseases of cerebrum which lead to the development of dementia. Because the exact causes of contraction of Alzheimer's disease (AD) are unknown, there is no adequate etiotropic therapy for this serious disease. Modern drugs present on the market, including cholinesterase inhibitors and NMDA antagonists, only alleviate symptoms without affecting the progression of AD. The review presents the results of modern studies confirming the significant contribution of gonadotropinreleasing hormone, gonadotropins and sex steroids to the development of mental aging. It is emphasized that the study of the role of the hypothalamic-pituitary-gonadal system in the etiopathogenesis of AD is certainly a promising area of psychoneuroendocrinology, which, perhaps, will lead to the development of new approaches to the treatment of this neurodegenerative disease. The contradictoriness of the data of a number of studies is noted and discussed.

scholarly journals Alzheimer's disease: the potential therapeutic role of the natural antibiotic amyloid-β peptide

2016 ◽  
Vol 6 (5) ◽  
pp. 345-348 ◽  
Author(s):  
Deepak Kumar Vijaya Kumar ◽  
William A Eimer ◽  
Rudolph E Tanzi ◽  
Robert D Moir
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Amyloid Β ◽  
Amyloid Β Peptide ◽  
Therapeutic Role ◽  
Potential Therapeutic Role

The Emerging Therapeutic Role of NGF in Alzheimer’s Disease

2016 ◽  
Vol 41 (6) ◽  
pp. 1211-1218 ◽  
Author(s):  
Chao-Jin Xu ◽  
Jun-Ling Wang ◽  
Wei-Lin Jin
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Therapeutic Role

scholarly journals P3-070: THERAPEUTIC ROLE OF METFORMIN IN PRECLINICAL Aβ(1-42) INDUCED RAT MODELS OF ALZHEIMER'S DISEASE

2019 ◽  
Vol 15 ◽  
pp. P953-P953
Author(s):  
Bikash Medhi ◽  
Harish Kumar ◽  
Amitava Chakrabarti ◽  
Manish Modi ◽  
B.D. Radotra ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Therapeutic Role ◽  
Rat Models
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