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2022 ◽  
Vol 316 ◽  
pp. 125800
Author(s):  
Muhan Wang ◽  
Kaixuan Zhang ◽  
Xiang Ji ◽  
Pan Wang ◽  
Hongyan Ma ◽  
...  

2021 ◽  
Author(s):  
Tatja Scholte

Site-specific installations are created for a specific location and are usually intended as temporary artworks. The Perpetuation of Site-Specific Installation Artworks in Museums. Staging Contemporary Art shows that these artworks consist of more than a singular manifestation and that their lifespan is often extended. This book provides an in-depth account of the paradoxical situation when site-specific installations are being preserved and put on display in a museum context. Tatja Scholte offers a conceptual framework for scholars and professionals in order to better understand the transformative nature of site-specific installation art and to support decision-making in museums as to conserving and presenting these artworks over time. The case studies provide insight into the diversity of artistic production over the last forty years. They explore how site-specific installations gain new meanings and forms in a museum context, and, vice versa, how these artworks become agents for change of professional routines and museum strategies.


2021 ◽  
Author(s):  
Anna S. Weiss ◽  
Anna G. Burrichter ◽  
Abilash Chakravarthy Durai Raj ◽  
Alexandra von Strempel ◽  
Chen Meng ◽  
...  

AbstractA key challenge in microbiome research is to predict the functionality of microbial communities based on community membership and (meta)-genomic data. As central microbiota functions are determined by bacterial community networks, it is important to gain insight into the principles that govern bacteria-bacteria interactions. Here, we focused on the growth and metabolic interactions of the Oligo-Mouse-Microbiota (OMM12) synthetic bacterial community, which is increasingly used as a model system in gut microbiome research. Using a bottom-up approach, we uncovered the directionality of strain-strain interactions in mono- and pairwise co-culture experiments as well as in community batch culture. Metabolic network reconstruction in combination with metabolomics analysis of bacterial culture supernatants provided insights into the metabolic potential and activity of the individual community members. Thereby, we could show that the OMM12 interaction network is shaped by both exploitative and interference competition in vitro in nutrient-rich culture media and demonstrate how community structure can be shifted by changing the nutritional environment. In particular, Enterococcus faecalis KB1 was identified as an important driver of community composition by affecting the abundance of several other consortium members in vitro. As a result, this study gives fundamental insight into key drivers and mechanistic basis of the OMM12 interaction network in vitro, which serves as a knowledge base for future mechanistic in vivo studies.


Biomolecules ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 1809
Author(s):  
Cyrille Sabot ◽  
Péter Kele

The selective functionalization of biomolecules such as proteins, nucleic acids, lipids or carbohydrates is a focus of persistent interest due to their widespread use, ranging from basic chemical biology research to gain insight into biological processes to the most promising biomedical applications, including the development of diagnostics or targeted therapies [...]


Bioengineered ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 9847-9859
Author(s):  
Rahul Saini ◽  
Carlos Saul Osorio-Gonzalez ◽  
Satinder Kaur Brar ◽  
Raymond Kwong

2021 ◽  
Author(s):  
Anna G. M. Temp ◽  
Elisabeth Kasper ◽  
Stefan Vielhaber ◽  
Judith Machts ◽  
Andreas Hermann ◽  
...  

ChemTexts ◽  
2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Baoxin Zhang ◽  
Dilver Peña Fuentes ◽  
Armin Börner

AbstractHydroformylation is one of the most important homogeneously catalyzed reactions on an industrial scale. The manufacture of bulk chemicals clearly dominates. Large cobalt- and rhodium-based processes are mature technologies that have been developed over the past 80 years. Meanwhile, the potential of hydroformylation for the production of fine chemicals (perfumes, pharmaceuticals) has also been recognized. This review gives insight into the state-of-the-art of the reaction and its development. It commences with some remarks on the accidental discovery by the German chemist Otto Roelen within the historical and personal framework of the Fischer–Tropsch process, followed by the mechanistic basics of the catalytic cycle, metals used for the catalyst as well as their organic ligands. In addition, the stability of ligands and catalysts is addressed. The huge potential of this transformation is demonstrated using a variety of substrates. Finally, the use of some surrogates for syngas is discussed.


2021 ◽  
Author(s):  
Ruichen Dong ◽  
Tian Zhang ◽  
Jiyuan Liu ◽  
Huan Li ◽  
Deji Hu ◽  
...  

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