Phase‐Transfer Catalytic Strategy: Rapid Synthesis of Spiro‐Fused Heterocycles, Integrated with Four Pharmacophores‐Succinimide, Pyrrolidine, Oxindole, and Trifluoromethyl Group

2020 ◽  
Author(s):  
Zheng‐Jun Chen ◽  
Wei Liang ◽  
Zhuo Chen ◽  
Lin Chen
Keyword(s):  
Phase Transfer ◽  
Trifluoromethyl Group ◽  
Rapid Synthesis ◽  
Fused Heterocycles

Phase transfer-driven rapid and complete ligand exchange for molecular assembly of phospholipid bilayers on aqueous gold nanocrystals

2019 ◽  
Vol 55 (22) ◽  
pp. 3195-3198 ◽  
Author(s):  
Youngjae Lee ◽  
Jungwoo Jang ◽  
Jinho Yoon ◽  
Jeong-Woo Choi ◽  
Inhee Choi ◽  
...  
Keyword(s):  
Ligand Exchange ◽  
Phase Transfer ◽  
Molecular Assembly ◽  
Phospholipid Bilayers ◽  
Phospholipid Bilayer ◽  
Rapid Synthesis ◽  
Exchange Method ◽  
Gold Nanocrystals

A phase transfer-mediated ligand exchange method is developed for highly selective and rapid synthesis of colloidal phospholipid bilayer-coated gold nanocrystals.

Highly diastereo- and enantioselective organocatalytic synthesis of trifluoromethylated erythritols based on the in situ generation of unstable trifluoroacetaldehyde

2021 ◽  
Author(s):  
Kazumasa Funabiki ◽  
Toshiya Gotoh ◽  
Ryunosuke Kani ◽  
Toshiyasu Inuzuka ◽  
Yasuhiro Kubota
Keyword(s):  
Trifluoromethyl Group ◽  
In Situ Generation

A highly diastereo- and enantioselective organocatalytic method to synthesise erythritols bearing a trifluoromethyl group has been investigated.

Modified Solid-Phase Methods for the Rapid Synthesis of Opioid Peptides

1991 ◽  
Author(s):  
Richard A. Houghten ◽  
◽  
John M. Ostresh ◽  
Suzanne M. Pratt
Keyword(s):  
Opioid Peptides ◽  
Solid Phase ◽  
Rapid Synthesis

Exogenous Directing Group Free, Ligand-Enabled gamma-C(sp3)–H Arylation of Free Primary Aliphatic Amines and α-Amino Esters

2019 ◽  
Author(s):  
Yongzheng Ding ◽  
Shuai Fan ◽  
Xiaoxi Chen ◽  
yuzhen gao ◽  
Gang Li
Keyword(s):  
Amino Acids ◽  
Large Scale ◽  
Free Ligand ◽  
Aliphatic Amines ◽  
Rapid Synthesis ◽  
Amino Esters ◽  
Directing Group ◽  
Large Scale Synthesis ◽  
Primary Aliphatic Amines

A Pdᴵᴵ-catalyzed, ligand-enabled gamma-C(sp3)–H arylation of free primary aliphatic amines and amino esters without using an exogenous directing group is reported. This reaction is compatible with unhindered free aliphatic amines, and it is also be applicable to the rapid synthesis of biologically and synthetically valuable unnatural α-amino acids. Large scale synthesis is also feasible using this method.<br>

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