Biospecific interaction (affinity) CEC and affinity nano-LC

2007 ◽  
Vol 28 (1-2) ◽  
pp. 89-98 ◽  
Author(s):  
Fred M. Okanda ◽  
Ziad El Rassi
Keyword(s):  
Biospecific Interaction

scholarly journals Highly Sensitive Detection of CA 125 Protein with the Use of an n-Type Nanowire Biosensor

Biosensors ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 210
Author(s):  
Kristina A. Malsagova ◽  
Tatyana O. Pleshakova ◽  
Rafael A. Galiullin ◽  
Andrey F. Kozlov ◽  
Ivan D. Shumov ◽  
...  
Keyword(s):  
Protein Detection ◽  
Covalent Immobilization ◽  
Silicon On Insulator ◽  
Target Protein ◽  
Ca 125 ◽  
Minimum Concentration ◽  
Immobilized Antibodies ◽  
Highly Sensitive ◽  
Highly Sensitive Detection ◽  
Biospecific Interaction

The detection of CA 125 protein in a solution using a silicon-on-insulator (SOI)-nanowire biosensor with n-type chip has been experimentally demonstrated. The surface of nanowires was modified by covalent immobilization of antibodies against CA 125 in order to provide the biospecificity of the target protein detection. We have demonstrated that the biosensor signal, which results from the biospecific interaction between CA 125 and the covalently immobilized antibodies, increases with the increase in the protein concentration. At that, the minimum concentration, at which the target protein was detectable with the SOI-nanowire biosensor, amounted to 1.5 × 10−16 M.

Amperometric glucose biosensor based on glucose oxidase–lectin biospecific interaction

2013 ◽  
Vol 52 (3) ◽  
pp. 134-140 ◽  
Author(s):  
Juanjuan Zhang ◽  
Chengyan Wang ◽  
Shihong Chen ◽  
Dehua Yuan ◽  
Xia Zhong
Keyword(s):  
Glucose Oxidase ◽  
Glucose Biosensor ◽  
Biospecific Interaction
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