Demystifying the diagnostic criteria of indolent systemic mastocytosis

2021 ◽  
Author(s):  
Federica Irene Grifoni ◽  
Mariarita Sciumè ◽  
Giusy Ceparano ◽  
Marco Lavezzari ◽  
Giulia Galassi ◽  
...  
Keyword(s):  
Diagnostic Criteria ◽  
Systemic Mastocytosis ◽  
Indolent Systemic Mastocytosis

scholarly journals Routine abdominal ultrasonography has limited value in the care for patients with indolent systemic mastocytosis

Hematology ◽  
2017 ◽  
Vol 22 (9) ◽  
pp. 544-547 ◽  
Author(s):  
C. L. de Mol ◽  
M. A. W. Hermans ◽  
R. Gerth van Wijk ◽  
P. M. van Hagen ◽  
P. L. A. van Daele
Keyword(s):  
Systemic Mastocytosis ◽  
Abdominal Ultrasonography ◽  
Indolent Systemic Mastocytosis

KIT D816V mutation burden does not correlate to clinical manifestations of indolent systemic mastocytosis

2013 ◽  
Vol 132 (3) ◽  
pp. 723-728 ◽  
Author(s):  
Sigurd Broesby-Olsen ◽  
Thomas Kristensen ◽  
Hanne Vestergaard ◽  
Kim Brixen ◽  
Michael Boe Møller ◽  
...  
Keyword(s):  
Systemic Mastocytosis ◽  
Clinical Manifestations ◽  
Mutation Burden ◽  
Indolent Systemic Mastocytosis ◽  
Kit D816v

scholarly journals Systemic mastocytosis with subcutaneous hemorrhage and edema in a Greyhound dog: case report and review of diagnostic criteria

2020 ◽  
Vol 33 (1) ◽  
pp. 95-100
Author(s):  
Alexander Aceino ◽  
Unity Jeffery ◽  
Julie Piccione ◽  
Carolyn L. Hodo
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Diagnostic Criteria ◽  
Complete Blood Count ◽  
Systemic Mastocytosis ◽  
Mast Cell Tumors ◽  
Multiple Organs ◽  
Subcutaneous Edema ◽  
Diagnostic Framework ◽  
Criteria For Diagnosis

Systemic mastocytosis, characterized by infiltration of multiple organs by neoplastic mast cells, is a well-described entity in human medicine with specific criteria for diagnosis, but is ill defined in veterinary literature. Hemostatic disorders are reported in humans affected by systemic mastocytosis but have not been well described in veterinary literature. A 5-y-old, spayed female Greyhound dog had a 1-mo history of progressive ventral cutaneous edema, hemorrhage, and pain. Cytology of an antemortem aspirate from the subcutis of the ventral abdomen was suggestive of mast cell neoplasia, but no discrete mass was present. The dog was euthanized and submitted for autopsy; marked subcutaneous edema and hemorrhage were confirmed. The ventral abdominal panniculus and dermis superficial to the panniculus carnosus were infiltrated by a dense sheet of neoplastic mast cells. The neoplastic cells contained toluidine blue–positive granules and formed aggregates within the bone marrow and several visceral organs, including the liver, spleen, heart, and kidney. Diffuse edema and hemorrhage is an unusual presentation of mast cell tumors in dogs. Antemortem tests, including complete blood count, coagulation profile, and viscoelastic coagulation testing, were suggestive of a primary hemostatic defect. We discuss here the diagnostic criteria used in humans, how these can be applied to veterinary patients, and the limitations of the current diagnostic framework.

scholarly journals PRO142 PSYCHOMETRIC PERFORMANCE OF THE INDOLENT SYSTEMIC MASTOCYTOSIS SYMPTOM ASSESSMENT FORM (ISM-SAF)

2019 ◽  
Vol 22 ◽  
pp. S867-S868
Author(s):  
A. Shields ◽  
F. Taylor ◽  
R. Lamoureux ◽  
B. Padilla ◽  
K. Severson ◽  
...  
Keyword(s):  
Systemic Mastocytosis ◽  
Symptom Assessment ◽  
Psychometric Performance ◽  
Indolent Systemic Mastocytosis

Indolent systemic mastocytosis: is there a reliable radiographic pattern?

2012 ◽  
Vol 42 (8) ◽  
pp. 1017-1020
Author(s):  
Flávia Silva Braga ◽  
Gabriel Antônio de Oliviera ◽  
Adriana Maria Fonseca de Melo ◽  
Lívia Guidoni de Assis Barbosa ◽  
João Vinícius Cremasco Fraga
Keyword(s):  
Systemic Mastocytosis ◽  
Indolent Systemic Mastocytosis

Indolent systemic mastocytosis associated with multiple myeloma: A rare coexistence

2017 ◽  
Vol 48 (4) ◽  
pp. 364-368
Author(s):  
Karolina Chromik ◽  
Grzegorz Helbig ◽  
Joanna Dziaczkowska-Suszek ◽  
Anna Kopińska ◽  
Krzysztof Woźniczka ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Systemic Mastocytosis ◽  
Indolent Systemic Mastocytosis

Indolent systemic mastocytosis associated with atypical small lymphocytic lymphoma: a rare form of concomitant lymphoproliferative disease

2008 ◽  
Vol 39 (6) ◽  
pp. 917-924 ◽  
Author(s):  
Alexander W. Hauswirth ◽  
Manuela Födinger ◽  
Marika Fritz ◽  
Leonhard Müllauer ◽  
Ingrid Simonitsch-Klupp ◽  
...  
Keyword(s):  
Systemic Mastocytosis ◽  
Lymphoproliferative Disease ◽  
Small Lymphocytic Lymphoma ◽  
Rare Form ◽  
Indolent Systemic Mastocytosis

Heterogeneity of mast cells in mastocytosis and inhibitory effect of ketotifen and ranitidine on indolent systemic mastocytosis

1997 ◽  
Vol 100 (6) ◽  
pp. S25-S32 ◽  
Author(s):  
Motohiro Kurosawa ◽  
Hiroo Amano ◽  
Naotomo Kanbe ◽  
Sachiko Akimoto ◽  
Yuko Takeuchia ◽  
...  
Keyword(s):  
Mast Cells ◽  
Systemic Mastocytosis ◽  
Inhibitory Effect ◽  
Indolent Systemic Mastocytosis
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