Epstein-Barr virus-induced membrane antigens: Immunochemical characterization of triton X-100 solubilized viral membrane antigens from EBV-superinfected raji cells

1979 ◽  
Vol 23 (6) ◽  
pp. 808-817 ◽  
Author(s):  
Louis F. Qualtiere ◽  
Gary R. Pearson
1980 ◽  
Vol 88 (1) ◽  
pp. 52-57 ◽  
Author(s):  
Gregory D. Mathew ◽  
Louis F. Qualtiere ◽  
H. Bryan Neel ◽  
Gary R. Pearson

IgA immunoglobulin fractions containing antibodies to Epstein-Barr virus (EBV)-induced membrane antigens were isolated from the sera of two patients with nasopharyngeal carcinoma (NPC), from one non-NPC patient, and from three persons with sera negative for IgA antibodies. IgA antibodies were not cytotoxic against cells expressing EBV-induced membrane antigens in the antibody-dependent cellular cytotoxicity (ADCC) assay. However, IgA antibodies blocked IgG-mediated ADCC, which indicated that these antibodies could serve as a blocking “factor” in patients with disease and, therefore, were potentially detrimental to the host.


1986 ◽  
Vol 57 (3) ◽  
pp. 1105-1112 ◽  
Author(s):  
M de Turenne-Tessier ◽  
T Ooka ◽  
G de The ◽  
J Daillie

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