Rapid, divergent changes in spinal and forearm bone density following short-term intravenous treatment of paget's disease with pamidronate disodium

2009 ◽  
Vol 8 (2) ◽  
pp. 209-217 ◽  
Author(s):  
Roger I. Price ◽  
Donald H. Gutteridge ◽  
Bronwyn G.A. Stuckey ◽  
G. Neil Kent ◽  
Robert W. Retallack ◽  
...  
Keyword(s):  
Bone Density ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Short Term ◽  
Intravenous Treatment ◽  
Pamidronate Disodium ◽  
Forearm Bone

Skeletal Blood Flow in Paget's Disease of Bone and its Response to Calcitonin Therapy

1978 ◽  
Vol 54 (1) ◽  
pp. 69-74 ◽  
Author(s):  
R. Wootton ◽  
J. Reeve ◽  
E. Spellacy ◽  
M. Tellez-Yudilevich
Keyword(s):  
Alkaline Phosphatase ◽  
Blood Flow ◽  
Serum Alkaline Phosphatase ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Short Term ◽  
Urinary Hydroxyproline ◽  
Rapid Fall ◽  
Hydroxyproline Excretion

1. Blood flow to the skeleton was measured by the 18F clearance method of Wootton, Reeve & Veall (1976) in 24 patients with untreated Paget's disease. In every patient but one, resting skeletal blood flow was increased. There was a significant positive correlation between skeletal blood flow and serum alkaline phosphatase and between skeletal blood flow and urinary total hydroxyproline excretion. 2. Fourteen patients were re-studied after they had received short-term (7 days or less) or long-term (7 weeks or more) calcitonin. Skeletal blood flow, alkaline phosphatase and urinary hydroxyproline excretion fell towards normal in every case. There was some evidence from the short-term studies that calcitonin produced a more rapid fall in skeletal blood flow than in alkaline phosphatase. 3. Glomerular filtration rate appeared to increase transiently in response to calcitonin.

Bone density as a parameter of Paget's disease

1982 ◽  
Vol 71 (3) ◽  
pp. 57-59
Author(s):  
Paul T. Chandler ◽  
Sharon A. Chandler
Keyword(s):  
Bone Density ◽  
Paget’S Disease ◽  
Paget's Disease

Risedronate, a Highly Effective, Short-Term Oral Treatment for Paget's Disease: A Dose-Response Study

1999 ◽  
Vol 64 (2) ◽  
pp. 93-99 ◽  
Author(s):  
J. P. Brown ◽  
D. J. Hosking ◽  
L.-G. Ste-Marie ◽  
C. C. Johnston, Jr ◽  
J.-Y. Reginster ◽  
...  
Keyword(s):  
Dose Response ◽  
Oral Treatment ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Short Term ◽  
Highly Effective ◽  
Dose Response Study

scholarly journals Effective short term treatment of Paget's disease with oral etidronate.

BMJ ◽  
1986 ◽  
Vol 292 (6513) ◽  
pp. 79-80 ◽  
Author(s):  
C J Preston ◽  
A J Yates ◽  
M N Beneton ◽  
R G Russell ◽  
R E Gray ◽  
...  
Keyword(s):  
Paget’S Disease ◽  
Paget's Disease ◽  
Term Treatment ◽  
Short Term ◽  
Short Term Treatment

Clinical, biochemical, hematologic, and radiographic responses in Paget's disease following intravenous pamidronate disodium: A 2-year study

Bone ◽  
1996 ◽  
Vol 19 (4) ◽  
pp. 387-394 ◽  
Author(s):  
D.H. Gutteridge ◽  
R.W. Retallack ◽  
L.C. Ward ◽  
B.G.A. Stuckey ◽  
G.O. Stewart ◽  
...  
Keyword(s):  
Paget’S Disease ◽  
Paget's Disease ◽  
Intravenous Pamidronate ◽  
Pamidronate Disodium
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