Development of tyrosine aminotransferase in perinatal rat liver: Changes in functional messenger RNA and the role of inducing hormones

1983 ◽  
Vol 21 (1) ◽  
pp. 47-61 ◽  
Author(s):  
Stephanie T. Perry ◽  
Robin Rothrock ◽  
Kenneth R. Isham ◽  
Kai-Lin Lee ◽  
Francis T. Kenney
Keyword(s):  
Rat Liver ◽  
Messenger Rna ◽  
Tyrosine Aminotransferase ◽  
Liver Changes

DDT-INDUCED METABOLIC CHANGES IN RAT LIVER

1967 ◽  
Vol 45 (12) ◽  
pp. 1809-1817 ◽  
Author(s):  
Emilio Sánchez
Keyword(s):  
Rat Liver ◽  
Liver Cell ◽  
Messenger Rna ◽  
Reduced Form ◽  
Liver Protein ◽  
Total Glutathione ◽  
Metabolizing Enzymes ◽  
Free System ◽  
Relative Inhibition

Administration of DDT to rats resulted in an increase in the rate of incorporation of DL-leucine-1-14C into proteins by a liver cell-free system. This effect was paralleled by an increase in the activity of microsomal DDT-metabolizing enzymes and in total liver protein, as well as by increased synthesis of RNA. The level of total glutathione in liver and blood was not modified, but the amount of the oxidized form was increased at the expense of the reduced form. Phenobarbital or hydrocortisone also increased the levels of microsomal DDT-metabolizing enzymes but their combination with DDT produced a relative inhibition. The role of DDT as an enzyme inducer and the possibility that changes in RNA correspond to increased synthesis of messenger RNA are discussed. These results confirm and extend previous ones obtained in this laboratory.

scholarly journals The role of thyroxine in the regulation of translatable messenger RNA for α2uglobulin in rat liver

FEBS Letters ◽  
1976 ◽  
Vol 64 (2) ◽  
pp. 396-399 ◽  
Author(s):  
K. Arun Roy ◽  
Michael J. Schiop ◽  
Donald J. Dowbenko
Keyword(s):  
Rat Liver ◽  
Messenger Rna

scholarly journals Purification and Properties of Rat Liver Tyrosine Aminotransferase

1969 ◽  
Vol 244 (13) ◽  
pp. 3618-3624 ◽  
Author(s):  
F A Valeriote ◽  
F Auricchio ◽  
G M Tomkins ◽  
D Riley
Keyword(s):  
Rat Liver ◽  
Tyrosine Aminotransferase ◽  
Purification And Properties

scholarly journals Regulation of Tyrosine Aminotransferase in Rat Liver

1973 ◽  
Vol 248 (13) ◽  
pp. 4528-4531
Author(s):  
Ronald W. Johnson ◽  
Francis T. Kenney
Keyword(s):  
Rat Liver ◽  
Tyrosine Aminotransferase
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