scholarly journals New fractionations in breast cancer: a dosimetric study of 3D‐CRT versus VMAT

2021 ◽  
Author(s):  
Antonio Piras ◽  
Sebastiano Menna ◽  
Andrea D’Aviero ◽  
Fabio Marazzi ◽  
Alberto Mazzini ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Dosimetric Study ◽  
3D Crt

Second cancer risk after 3D-CRT, IMRT and VMAT for breast cancer

2014 ◽  
Vol 110 (3) ◽  
pp. 471-476 ◽  
Author(s):  
Yasser Abo-Madyan ◽  
Muhammad Hammad Aziz ◽  
Moamen M.O.M. Aly ◽  
Frank Schneider ◽  
Elena Sperk ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Risk ◽  
Second Cancer ◽  
Second Cancer Risk ◽  
3D Crt

scholarly journals Developing of predictive models for pneumonitis with forward variable selection and LASSO logistic model for breast cancer patients treated with 3D-CRT

2018 ◽  
Vol 24 (4) ◽  
pp. 149-156 ◽  
Author(s):  
Maede Hasan Abdali ◽  
Karim Khoshgard ◽  
Abdolazim Sedighi Pashaki
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Lung Volume ◽  
Probability Model ◽  
Pulmonary Function Tests ◽  
Normal Tissue Complication Probability ◽  
Breast Cancer Patients ◽  
Predictive Parameters ◽  
Mean Lung Dose ◽  
3D Crt

Abstract Purpose: To develop a multiple logistic regression model as normal tissue complication probability model by least absolute shrinkage and selection operator (LASSO) technique in breast cancer patients treated with three-dimensional conformal radiation therapy (3D-CRT), we focused on the changes of pulmonary function tests to achieve the optimal predictive parameters for the occurrence of symptomatic radiation pneumonitis (SRP). Materials and methods: Dosimetric and spirometry data of 60 breast cancer patients were analyzed. Pulmonary function tests were done before RT, after completion of RT, 3, and 6 months after RT. Multiple logistic regression model was used to obtain the effective predictive parameters. Forward selection method was applied in NTCP model to determine the effective risk factors from obtained different parameters. Results: Symptomatic radiation pneumonitis was observed in five patients. Significant changes in pulmonary parameters have been observed at six months after RT. The parameters of mean lung dose (MLD), bridge separation (BS), mean irradiated lung volume (ILVmean), and the percentage of the ipsilateral lung volume that received dose of 20 Gy (IV20) introduced as risk factors using the LASSO technique for SRP in a multiple normal tissue complication probability model in breast cancer patients treated with 3D-CRT. The BS, central lung distance (CLD) and ILV in tangential field have obtained as 23.5 (20.9-26.0) cm, 2.4 (1.5-3.3) cm, and 12.4 (10.6-14.3) % of lung volume in radiation field in patients without pulmonary complication, respectively. Conclusion: The results showed that if BS, CLD, and ILV are more than 23 cm, 2 cm, and 12%, respectively, so incidence of SRP in the patients will be considerable. Our multiple NTCP LASSO model for breast cancer patients treated with 3D-CRT showed that in order to have minimum probability of SRP occurrence, parameters of BS, IV20, ILV and especially MLD would be kept in minimum levels. Considering dose-volume histogram, the mean lung dose factor is most important parameter which minimizing it in treatment planning, minimizes the probability of SRP and consequently improves the quality of life in breast cancer patients.

156. Dosimetric comparison between 3D-CRT, Field in Field and VMAT techniques in the adjuvant radiotherapy treatment of breast cancer

2018 ◽  
Vol 56 ◽  
pp. 160-161
Author(s):  
M.C. De Nile ◽  
L. Perna ◽  
P. Mangili ◽  
P. Signorotto ◽  
B. Longobardi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adjuvant Radiotherapy ◽  
Dosimetric Comparison ◽  
Radiotherapy Treatment ◽  
3D Crt

scholarly journals EP-1915: IMRT for breast cancer: a comparative dosimetric study between Tomotherapy, VMAT and proton therapy

2018 ◽  
Vol 127 ◽  
pp. S1040
Author(s):  
C. Adrien ◽  
L. Bartolucci ◽  
M. Lejars ◽  
M. Vaillant ◽  
S. Ribes ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Proton Therapy ◽  
Dosimetric Study
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