Evaluation of 3D-CRT, IMRT and VMAT radiotherapy plans for left breast cancer based on clinical dosimetric study

2016 ◽  
Vol 54 ◽  
pp. 1-5 ◽  
Author(s):  
Haiyun Liu ◽  
Xinde Chen ◽  
Zhijian He ◽  
Jun Li
Keyword(s):  
Breast Cancer ◽  
Left Breast ◽  
Dosimetric Study ◽  
3D Crt

scholarly journals New fractionations in breast cancer: a dosimetric study of 3D‐CRT versus VMAT

2021 ◽  
Author(s):  
Antonio Piras ◽  
Sebastiano Menna ◽  
Andrea D’Aviero ◽  
Fabio Marazzi ◽  
Alberto Mazzini ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Dosimetric Study ◽  
3D Crt

scholarly journals Analysis Of Dose At 3D-Crt And Imrt Techniques In Left Breast Cancer Case With Hypofractionation Using Deep Inspiration Breath-Hold (Dibh)

2021 ◽  
Author(s):  
Samsun - ◽  
Muhammad Arif Arif ◽  
Gregorius Septayudha Septayudha
Keyword(s):  
Breast Cancer ◽  
At Risk ◽  
Organs At Risk ◽  
Left Breast ◽  
Breath Hold ◽  
Tolerance Limits ◽  
Deep Inspiration Breath Hold ◽  
Organ At Risk ◽  
The Difference ◽  
3D Crt

Abstract In terms of breast cancer radiation treatment, it has radiation using the 3D-Conformal Radiotherapy (3D-CRT) technique and the continuation of the 3D-CRT technique, namely the Intensity Modulated Radiation Therapy (IMRT) technique. This study aims to evaluate the dosage aspects of PTV and OAR between the 3D-CRT and IMRT techniques in cases of left breast cancer with hypofractionation using the Deep Inspiration Breath Hold (DIBH) method using the Conformity Index (CI) and Homogeneity Index (H.I.) and H.I. organ at risk uses tolerance limits. This type of research is comparative quantitative with ten samples with primary data conducted at Siloam T.B. Hospital. Simatupang from November 2019 to April 2020. The research was carried out in the form of radiation planning with 3D-CRT techniques and IMRT techniques, and the results of planning both techniques were evaluated between 3D-CRT techniques and IMRT techniques through PTV evaluations using CI and H.I. values. Furthermore, the organs at risk use tolerance limits on each organ. The results showed the assessment between 3D-CRT and IMRT on PTV and organs at risk received different doses. The PTV shows the CI value, which is almost the same as the difference of 0.034, and there is a slight difference in H.I. with an average value in the IMRT technique of 0.07 and 3D-CRT of 0.11, and it can be seen that the IMRT is slightly superior because the excellent H.I. value is the closest to 0. Then at the dose of organ at risk received by the sample, the 3D-CRT technique is slightly superior by obtaining a lower dose that obtains the difference in the heart by 0.53%, lung by 3.46%, spinal cord by 6.51 Gy, esophagus at 4.5 Gy, and larynx at 5.18 Gy.

scholarly journals So sánh các thông số liều lượng của kỹ thuật vmat và 3d-crt trong xạ trị ung thư vú trái và hạch vùng

2020 ◽  
Author(s):  
Đình Long Nguyễn
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Volumetric Modulated Arc Therapy ◽  
Left Lung ◽  
Conformal Radiotherapy ◽  
Left Breast ◽  
Three Dimension ◽  
Breast Cancer Patients ◽  
Arc Therapy ◽  
3D Crt

COMPARISON OF DOSIMETRIC PARAMETERS OF VOLUMETRIC MODULATED ARC THERAPY AND THREE-DIMENSIONAL CONFORMAL RADIOTHERAPY FOR LEFT SIDE BREAST AND REGIONAL NODES Objective: Comparative study of dose parameters of Volumetric modulated arc therapy (VMAT) and three-dimension radiotherapy (3D-CRT) in patients after left breast surgery with radiation therapy with regional lymph nodes. Materials and Methods: Twenty-four plans of 12 left-breast cancer patients were treated with VMAT with 4 partial arc and 3D-CRT plans were added to compare each other, from 1/2018 to 3/2019 at the Vinmec TimesCity International Hospital. Results: The average coverage dose to the treatment volume (PTV) of VMAT plans is better than the 3D-CRT plan (99.10 ± 0.17 % compared to 98.7 ± 0.34 %; p = 0.01). Conformity index (CI), homogeneity index (HI) for VMAT plans also better results CI: 0.99 vs. 0.98; p = 0.26 and HI: 0.096 compared to 0.119; p = 0.02). Organs at risk, at low doses V5Gy, V10Gy VMAT plans do not avoid good doses by 3D-CRT plans: V5Gy for left lung (78.8 ± 4.6 % compared to 55.37 ± 4.38 %) and heart (77.15 ± 9.52 % compared to 19.15 ± 7.93 %) (p <0.001). However, at high doses, 3D-CRT plans are much higher than VMAT: Dose to left lung V20Gy (36.22 ± 3.9 % compared to 22.62 ± 2.43 %), V30Gy (30.6 ± 5.97 % compared to 11.77 ± 2.53 %) and V40Gy (24.73 ± 8.59 % compared to 3.63 ± 2.02 %) (P <0.001). Similarly, the cardiac arrival dose of the 3D-CRT plan is higher than that of VMAT: V20Gy (11.54 ± 5.83 % compared to 9.49 ± 6.00 %, p> 0.05), V30Gy (9.25 ± 5.56 % compared to 2.13 ± 1.89 %) and V40 Gy (7.54 ± 5.03 % compared with 0.2 ± 0.25 %). Dose to coronary arteries also decreased significantly for VMAT plans compared to 3D-CRT: V20Gy (0.8 ± 1.01 % compared to 27.29 ± 15.19 %) V30Gy (0.00 % compared to 23.09 ± 10.73 %). Conclusion: VMAT is dosimetrically superior to the 3D-CRT for left‑sided breast cancer patients with regional nodes by dose coverage to PTV and good ability to avoid heart and lung and coronary arteries than. Key words: Breast cancer, Postmastectomy radiotherapy, Three-dimension conformal radiotherapy, Volumetric modulated arc therapy.

scholarly journals EP-1948 Deep-inspiration breath-hold and freebreathing in left breast cancer irradiation:a dosimetric study

2019 ◽  
Vol 133 ◽  
pp. S1061-S1062
Author(s):  
D. Aiello ◽  
G.R. Borzì ◽  
L. Marino ◽  
V. Umina ◽  
A.M. Di Grazia
Keyword(s):  
Breast Cancer ◽  
Left Breast ◽  
Breath Hold ◽  
Deep Inspiration ◽  
Deep Inspiration Breath Hold ◽  
Dosimetric Study

scholarly journals A COMPARATIVE DOSIMETRIC STUDY OF LEFT SIDED BREAST CANCER AFTER BREAST CONSERVING SURGERY WITH 3D-CRT AND VMAT

2020 ◽  
Vol 8 (11) ◽  
pp. 1088-1093
Author(s):  
F. Kouhen ◽  
◽  
H.El Gouache ◽  
M. Bensediq ◽  
K. Saadi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Conformal Radiotherapy ◽  
Breast Conserving Surgery ◽  
Left Breast ◽  
Conformity Index ◽  
Clinical Value ◽  
Three Dimensional Conformal Radiotherapy ◽  
3D Crt

Purpose: This paper aims to compare dosimetric differences based between three-dimensional conformal radiotherapy (3D-CRT), and volumetric modulated arc therapy(VMAT) techniques of radiotherapy plans for postoperative left breast cancer after breast conserving surgery. Materials and Methods: Nineteen patients with left breast cancer who had received breast conserving surgery without nodal involvement. Two separate treatment plans with an identical isocenter were created to each patient: 3D radiotherapy plan with 2 tangent isocentric beams with field-in-field technique andVMAT plan with Two duplicate sets of partial arcs. Results: The VMAT plan showed superior to PTV dose conformity index (CI), homogeneity index (HI), protection of the ipsilateral lung, and heart compared with 3D plan. However, it increases significantly dose to the contralateral breast with D mean which were 0.1±0.003 Gy and 5.31±1.04 Gy, respectively. Conclusion: VMAT greatly decreases the radiation doses delivered to the OAR with maintained therapeutic efficacy.However, further studies evaluating the clinical outcome of treatments are needed to proof the clinical value of this radiation technique.

scholarly journals Deep-inspirational breath-hold (DIBH) technique in left-sided breast cancer: various aspects of clinical utility

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Szilvia Gaál ◽  
Zsuzsanna Kahán ◽  
Viktor Paczona ◽  
Renáta Kószó ◽  
Rita Drencsényi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Side Effects ◽  
Clinical Utility ◽  
Prospective Trial ◽  
Conformal Radiotherapy ◽  
Free Breathing ◽  
Left Breast ◽  
Breath Hold ◽  
Ipsilateral Lung ◽  
Breast Cancer Radiotherapy

Abstract Background Studying the clinical utility of deep-inspirational breath-hold (DIBH) in left breast cancer radiotherapy (RT) was aimed at focusing on dosimetry and feasibility aspects. Methods In this prospective trial all enrolled patients went through planning CT in supine position under both DIBH and free breathing (FB); in whole breast irradiation (WBI) cases prone CT was also taken. In 3-dimensional conformal radiotherapy (3DCRT) plans heart, left anterior descending coronary artery (LAD), ipsilateral lung and contralateral breast doses were analyzed. The acceptance of DIBH technique as reported by the patients and the staff was analyzed; post-RT side-effects including radiation lung changes (visual scores and lung density measurements) were collected. Results Among 130 enrolled patients 26 were not suitable for the technique while in 16, heart or LAD dose constraints were not met in the DIBH plans. Among 54 and 34 patients receiving WBI and postmastectomy/nodal RT, respectively with DIBH, mean heart dose (MHD) was reduced to < 50%, the heart V25 Gy to < 20%, the LAD mean dose to < 40% and the LAD maximum dose to about 50% as compared to that under FB; the magnitude of benefit was related to the relative increase of the ipsilateral lung volume at DIBH. Nevertheless, heart and LAD dose differences (DIBH vs. FB) individually varied. Among the WBI cases at least one heart/LAD dose parameter was more favorable in the prone or in the supine FB plan in 15 and 4 cases, respectively; differences were numerically small. All DIBH patients completed the RT, inter-fraction repositioning accuracy and radiation side-effects were similar to that of other breast RT techniques. Both the patients and radiographers were satisfied with the technique. Conclusions DIBH is an excellent heart sparing technique in breast RT, but about one-third of the patients do not benefit from that otherwise laborious procedure or benefit less than from an alternative method. Trial registration: retrospectively registered under ISRCTN14360721 (February 12, 2021)

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