Hepatitis delta virus cDNA sequence from an acutely HBV-infected chimpanzee: Sequence conservation in experimental animals

1991 ◽  
Vol 34 (4) ◽  
pp. 268-279 ◽  
Author(s):  
Ton Kos ◽  
Anco Molijn ◽  
Leen-Jan Van Doorn ◽  
Alex Van Belkum ◽  
Martin Dubbeld ◽  
...  
Virology ◽  
1993 ◽  
Vol 197 (1) ◽  
pp. 137-142 ◽  
Author(s):  
Fei-Ping Tai ◽  
Pei-Jer Chen ◽  
Fu-Lin Chang ◽  
Ding-Shinn Chen

1989 ◽  
Vol 63 (10) ◽  
pp. 4292-4297 ◽  
Author(s):  
C Sureau ◽  
J Taylor ◽  
M Chao ◽  
J W Eichberg ◽  
R E Lanford

2021 ◽  
pp. 104870
Author(s):  
Boris J.B. Beudeker ◽  
Jolanda J.C. Voermans ◽  
Corine.H. GeurtsvanKessel ◽  
Robert J. de Knegt ◽  
Tamara Kuhlemann ◽  
...  

2021 ◽  
Author(s):  
Kasthuri Prakash ◽  
Simon B. Larsson ◽  
Gustaf E. Rydell ◽  
Johan Ringlander ◽  
Catarina Skoglund ◽  
...  

Infection ◽  
1992 ◽  
Vol 20 (1) ◽  
pp. 43-44 ◽  
Author(s):  
T. Laskus ◽  
M. Radkowski ◽  
J. Slusarczyk ◽  
Grazyna Halama ◽  
Ewa Lupa ◽  
...  

2007 ◽  
Vol 82 (3) ◽  
pp. 1118-1127 ◽  
Author(s):  
Jinhong Chang ◽  
Xingcao Nie ◽  
Ho Eun Chang ◽  
Ziying Han ◽  
John Taylor

ABSTRACT Previous studies have indicated that the replication of the RNA genome of hepatitis delta virus (HDV) involves redirection of RNA polymerase II (Pol II), a host enzyme that normally uses DNA as a template. However, there has been some controversy about whether in one part of this HDV RNA transcription, a polymerase other than Pol II is involved. The present study applied a recently described cell system (293-HDV) of tetracycline-inducible HDV RNA replication to provide new data regarding the involvement of host polymerases in HDV transcription. The data generated with a nuclear run-on assay demonstrated that synthesis not only of genomic RNA but also of its complement, the antigenome, could be inhibited by low concentrations of amanitin specific for Pol II transcription. Subsequent studies used immunoprecipitation and rate-zonal sedimentation of nuclear extracts together with double immunostaining of 293-HDV cells, in order to examine the associations between Pol II and HDV RNAs, as well as the small delta antigen, an HDV-encoded protein known to be essential for replication. Findings include evidence that HDV replication is somehow able to direct the available delta antigen to sites in the nucleoplasm, almost exclusively colocalized with Pol II in what others have described as transcription factories.


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