The present paper addresses anatomically resolved protein networks
by using the Imaging Cycler Microscopy (ICM/TIS) [1,2]. ICM is
capable of resolving protein networks in intact anatomical structures
at a power of combinatorial molecular resolution of 65,553k
, where
k is the number of co-mapped proteins, e.g. 100 proteins [1-4]. This
method provides insight into the laws of the spatial communication
of large protein networks in health and disease, which is essential
for new therapy options in diseases.
Therapeutic Depletion of Axotomy Competent Cells in Amyotrophic Lateral
Sclerosis (ALS)
