Analysis of hearing preservation after endolymphatic mastoid sac surgery for Meniere's disease

2010 ◽  
Vol 120 (3) ◽  
pp. 591-597 ◽  
Author(s):  
Gordon H. Sun ◽  
Randal Leung ◽  
Ravi N. Samy ◽  
Jacob S. McAfee ◽  
Matthew J. Hearst ◽  
...  
2016 ◽  
Vol 131 (2) ◽  
pp. 144-149 ◽  
Author(s):  
R F Bento ◽  
J C Cisneros ◽  
A C De Oliveira Fonseca

AbstractObjective:To describe the results obtained with endolymphatic sac drainage in patients with Ménière's disease.Method:A retrospective case review study was conducted of 95 Ménière's disease patients who underwent endolymphatic sac drainage in a tertiary care referral centre, after failing a long course of medical management. The main outcome measures were vertigo control and hearing preservation.Results:In patients with unilateral disease, vertigo control was obtained in 94.3 per cent of patients. A significant improvement in cochlear function was seen in 14 per cent of patients, and hearing was preserved or improved in 88 per cent. For the bilateral group, vertigo control was obtained in 85.7 per cent of patients and cochlear function improved in 28 per cent. Hearing preservation was attained in 71 per cent of these patients.Conclusion:Endolymphatic sac drainage is a good surgical option for patients with incapacitating endolymphatic hydrops, providing a high percentage of vertigo control and hearing preservation.


2019 ◽  
Vol 130 (12) ◽  
pp. 2874-2878
Author(s):  
Maheer M. Masood ◽  
Douglas R. Farquhar ◽  
Kevin D. Brown ◽  
Harold C. Pillsbury ◽  
English R. King ◽  
...  

2021 ◽  
Vol 10 (23) ◽  
pp. 5581
Author(s):  
Seong-Hoon Bae ◽  
Jeon-Mi Lee ◽  
Hyun-Jin Lee ◽  
Gina Na ◽  
Sung-Huhn Kim

Chemical labyrinthectomy using gentamicin is a popular method for treating intractable vertigo attacks in Meniere’s disease. However, the risk of hearing loss remains a major concern for clinicians. We investigated the effect of simultaneous dexamethasone and gentamicin application on hearing preservation and vertigo control in patients with intractable unilateral Meniere’s disease. A single-institutional, prospective, single-blinded, randomized clinical trial was conducted. Gentamicin-soaked Gelfoam® was directly applied on the oval window following middle ear exploration. On the round window, dexamethasone-soaked Gelfoam® was applied in the gentamicin with dexamethasone group (GD group, n = 18), and saline-soaked Gelfoam® was applied in the gentamicin with sham reagent group (GO group, n = 19). The hearing change 8 weeks after the procedure and vertigo control 2–12 months after the procedure were investigated. The high-frequency hearing threshold was significantly increased in the GO group (p = 0.005 and 0.012 for 4 and 8 kHz, respectively), but not in the GD group. The short-term (2–6 months) vertigo control was more successful in the GD group (57.89% vs. 94.44%, p = 0.019), but long-term control (6–12 months) was insignificant. In conclusion, the combined application of gentamicin and dexamethasone in chemical labyrinthectomy is an effective method for protecting high-frequency hearing and vertigo control.


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