Evaluation of quantitative, efficient image reconstruction for VersaPET, a compact PET system

2020 ◽  
Vol 47 (7) ◽  
pp. 2852-2868
Author(s):  
Shouyi Wei ◽  
Paul Vaska

2011 ◽  
Author(s):  
YuKai Hung ◽  
Yun Dong ◽  
Felix R. Chern ◽  
Weichung Wang ◽  
Chien-Min Kao ◽  
...  


2006 ◽  
Author(s):  
Debashish Pal ◽  
Yuan-Chuan Tai ◽  
Martin Janecek ◽  
Heyu Wu ◽  
Joseph A. O'Sullivan


2016 ◽  
Vol 40 (5) ◽  
pp. 058201 ◽  
Author(s):  
Xiao-Yue Gu ◽  
Wei Zhou ◽  
Lin Li ◽  
Long Wei ◽  
Peng-Fei Yin ◽  
...  


1991 ◽  
Vol 36 (1) ◽  
pp. 35-46 ◽  
Author(s):  
M J Hogan ◽  
P J Harvey ◽  
D C Howse ◽  
B T A McKee






2004 ◽  
Vol 43 (03) ◽  
pp. 72-78 ◽  
Author(s):  
M. Henze ◽  
O. Bublitz ◽  
A. Werling ◽  
L. E. Adam ◽  
U. Haberkorn ◽  
...  

Summary Aim: Improvement of the spatial resolution in positron emission tomography (PET) by incorporation of the image-forming characteristics of the scanner into the process of iterative image reconstruction. Methods: All measurements were performed at the whole-body PET system ECAT EXACT HR+ in 3D mode. The acquired 3D sinograms were sorted into 2D sinograms by means of the Fourier rebinning (FORE) algorithm, which allows the usage of 2D algorithms for image reconstruction. The scanner characteristics were described by a spatially variant line-spread function (LSF), which was determined from activated copper-64 line sources. This information was used to model the physical degradation processes in PET measurements during the course of 2D image reconstruction with the iterative OSEM algorithm. To assess the performance of the high-resolution OSEM algorithm, phantom measurements performed at a cylinder phantom, the hotspot Jaszczack phantom, and the 3D Hoffmann brain phantom as well as different patient examinations were analyzed. Results: Scanner characteristics could be described by a Gaussian-shaped LSF with a full-width at half-maximum increasing from 4.8 mm at the center to 5.5 mm at a radial distance of 10.5 cm. Incorporation of the LSF into the iteration formula resulted in a markedly improved resolution of 3.0 and 3.5 mm, respectively. The evaluation of phantom and patient studies showed that the high-resolution OSEM algorithm not only lead to a better contrast resolution in the reconstructed activity distributions but also to an improved accuracy in the quantification of activity concentrations in small structures without leading to an amplification of image noise or even the occurrence of image artifacts. Conclusion: The spatial and contrast resolution of PET scans can markedly be improved by the presented image restauration algorithm, which is of special interest for the examination of both patients with brain disorders and small animals.



PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e50540 ◽  
Author(s):  
Cheng-Ying Chou ◽  
Yun Dong ◽  
Yukai Hung ◽  
Yu-Jiun Kao ◽  
Weichung Wang ◽  
...  


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