scholarly journals Transcranial direct current stimulation does not modulate motor cortex excitability in patients with amyotrophic lateral sclerosis

2011 ◽  
Vol 44 (1) ◽  
pp. 109-114 ◽  
Author(s):  
Moniek A.M. Munneke ◽  
Dick F. Stegeman ◽  
Yvonne A. Hengeveld ◽  
Jan J. Rongen ◽  
H. Jurgen Schelhaas ◽  
...  
2007 ◽  
Vol 35 (5) ◽  
pp. 620-624 ◽  
Author(s):  
Angelo Quartarone ◽  
Nicolas Lang ◽  
Vincenzo Rizzo ◽  
Sergio Bagnato ◽  
Francesca Morgante ◽  
...  

2016 ◽  
Vol 4 (15) ◽  
pp. e12884 ◽  
Author(s):  
Wolfgang Strube ◽  
Tilmann Bunse ◽  
Michael A. Nitsche ◽  
Alexandra Nikolaeva ◽  
Ulrich Palm ◽  
...  

Author(s):  
Vincent Cabibel ◽  
Makii Muthalib ◽  
Jérôme Froger ◽  
Stéphane Perrey

Repeated transcranial magnetic stimulation (rTMS) is a well-known clinical neuromodulation technique, but transcranial direct-current stimulation (tDCS) is rapidly growing interest for neurorehabilitation applications. Both methods (contralesional hemisphere inhibitory low-frequency: LF-rTMS or lesional hemisphere excitatory anodal: a-tDCS) have been employed to modify the interhemispheric imbalance following stroke. The aim of this pilot study was to compare aHD-tDCS (anodal high-definition tDCS) of the left M1 (2 mA, 20 min) and LF-rTMS of the right M1 (1 Hz, 20 min) to enhance excitability and reduce inhibition of the left primary motor cortex (M1) in five healthy subjects. Single-pulse TMS was used to elicit resting and active (low level muscle contraction, 5% of maximal electromyographic signal) motor-evoked potentials (MEPs) and cortical silent periods (CSPs) from the right and left extensor carpi radialis muscles at Baseline, immediately and 20 min (Post-Stim-20) after the end of each stimulation protocol. LF-rTMS or aHD-tDCS significantly increased right M1 resting and active MEP amplitude at Post-Stim-20 without any CSP modulation and with no difference between methods. In conclusion, this pilot study reported unexpected M1 excitability changes, which most likely stems from variability, which is a major concern in the field to consider.


2019 ◽  
Vol 49 (1) ◽  
pp. 19-25 ◽  
Author(s):  
Filippo Zappasodi ◽  
Gabriella Musumeci ◽  
Riccardo Navarra ◽  
Vincenzo Di Lazzaro ◽  
Massimo Caulo ◽  
...  

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