Mixed carboxylic acid anhydrides: II. Esterification of alcohols with the formic acid/acetic anhydride reaction mixture

1964 ◽  
Vol 83 (12) ◽  
pp. 1287-1293 ◽  
Author(s):  
W. Stevens ◽  
A. van Es
Keyword(s):  
Carboxylic Acid ◽  
Acetic Anhydride ◽  
Formic Acid ◽  
Acid Anhydrides

scholarly journals Pitfalls in the use of carboxylic acid anhydrides for structural studies of nucleoprotein particles

1987 ◽  
Vol 241 (2) ◽  
pp. 621-623 ◽  
Author(s):  
M A Nieto ◽  
E Palacián
Keyword(s):  
Carboxylic Acid ◽  
Acetic Anhydride ◽  
Structural Studies ◽  
Amino Groups ◽  
Single Stranded Dna ◽  
Acid Anhydrides

During modification of protein amino groups with carboxylic acid anhydrides, these reagents cause a fall in pH, which can be prevented by addition of base. Although unmodified nucleosomal particles are not affected by the local transient changes in pH induced by the base (NaOH) added to prevent a fall in pH during modification, the nucleosomal particles modified by acetic anhydride are dissociated, with release of single-stranded DNA.

Carboxylic Acid Analogues of Fosmidomycin

2003 ◽  
Vol 58 (5) ◽  
pp. 457-461 ◽  
Author(s):  
Thomas Kurz ◽  
Detlef Geffken ◽  
Claudia Wackendorff
Keyword(s):  
Carboxylic Acid ◽  
Acetic Anhydride ◽  
Formic Acid ◽  
Butyric Acid ◽  
Catalytic Hydrogenation ◽  
Methylene Chloride ◽  
Benzyl Ester ◽  
Acid Chlorides ◽  
Chloride Treatment

N-Alkylation of N-Boc-O-benzylhydroxylamine (1) with benzyl 4-bromobutyrate (2) in DMF gave N,O-bisprotected benzyl 4-hydroxyamino-butyrate (3), which was converted into 4-benzyloxyamino-butyric acid benzyl ester (4) with TFA in methylene chloride. Treatment of 4 with formic acid/acetic anhydride or various acid chlorides followed by catalytic hydrogenation led to 4-(N-acyl-N-hydroxyamino)-butyric acids 6.

An Investigation of the Preparation and Reactions of trans-3, 4-Dihydroxycyclohexyl Carbinol as a Cellulose Model Compound

1969 ◽  
Vol 39 (7) ◽  
pp. 638-647
Author(s):  
John J. Porter ◽  
Philip A. Spanninger
Keyword(s):  
Gas Chromatography ◽  
Carboxylic Acid ◽  
Acetic Anhydride ◽  
Formic Acid ◽  
Infrared Spectra ◽  
Model Compound ◽  
Periodate Oxidation ◽  
Melting Points ◽  
Boiling Points ◽  
Rate Of Reaction

The synthesis of the fully equatorial form of trans-3,4-dihydroxycyclohexyl carbinol was achieved and proof of its configuration is presented. The equatorial epimer was prepared from 3-cyclohexcne-1-carboxaldehyde which was oxidized to 3-cyclohexene-11-carboxylic acid, hydroxylated and esterified to give methyl trans-3,4-dihydroxycyclohexyl-1-carboxylate. This compound was converted to the fully equatorial configuration by the use of a base. Reduction of the epimeric ester yielded the desired model compound. Proof of stereochemistry of the model was obtained from infrared spectra, boiling and melting points, and gas chromatography. The boiling points of the epimers were in agreement with the von Auwers-Skita or Conformational Rule. The cellulose model compound was reacted in separate experiments with acetic anhydride, formic acid, and N-(methoxymethylol)acetamide. Gas chromatography was used to observe the rate of reaction and periodate oxidation to determine the amount of secondary hydroxyl reacted. The results indicated extensive participation of the secondary hydroxyls in all cases and correlated with the data reported for cellulose.

scholarly journals CC-stretched formic acid: isomerisation, dimerisation, and carboxylic acid complexation

2021 ◽  
Author(s):  
Katharina A. E. Meyer ◽  
Arman Nejad
Keyword(s):  
Carboxylic Acid ◽  
Formic Acid ◽  
Vibrational Band ◽  
Propiolic Acid

The cis–trans-isomerism of the propiolic acid monomer (HCC–COOH) is examined with linear Raman jet spectroscopy, yielding the first environment-free vibrational band centres of a higher-energy cis-rotamer beyond formic acid (HCOOH) in addition to all fundamentals and a large number of hot and combination/overtone bands of the trans-conformer.

ChemInform Abstract: Acylation of Hydroxyethyl Hydrazine by Carboxylic Acid Anhydrides.

1986 ◽  
Vol 17 (36) ◽  
Author(s):  
V. V. SHEVCHENKO ◽  
G. A. VASIL'EVSKAYA ◽  
N. S. KLIMENKO ◽  
S. N. LOSHKAREVA ◽  
T. S. KHRAMOVA
Keyword(s):  
Carboxylic Acid ◽  
Acid Anhydrides
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