Diastereoselective Synthesis of Vicinal Diamines by Aza-Michael Addition of Chiral Phenethylamine to Nitroalkenes

2018 ◽  
Vol 3 (34) ◽  
pp. 9916-9919
Author(s):  
Chunying Ma ◽  
Jianxun Du ◽  
Yuhua Liang ◽  
Wenhua Feng
Keyword(s):  
Michael Addition ◽  
Diastereoselective Synthesis ◽  
Vicinal Diamines

Uncatalyzed diastereoselective synthesis of alkyliminofurochromone-derived benzylmalononitriles via a three-component cascade reaction: competition between Diels–Alder cycloaddition and Michael addition

2021 ◽  
Author(s):  
Mohammad Bagher Teimouri ◽  
Zahra Mokhtare ◽  
Hamid Reza Khavasi
Keyword(s):  
Michael Addition ◽  
Heterocyclic Ring ◽  
Cascade Reaction ◽  
Diels Alder ◽  
Chemical Bonds ◽  
Diastereoselective Synthesis ◽  
Atom Economy ◽  
One Pot

Three new chemical bonds and three stereogenic centres and one heterocyclic ring were assembled stereoselectively in a convenient high atom-economy one-pot operation.

Diastereoselective synthesis of bicyclo[2.2.2]octanes by double Michael addition

1989 ◽  
Vol 30 (5) ◽  
pp. 547-550 ◽  
Author(s):  
Dietrich Spitzner ◽  
Peter Wagner ◽  
Arndt Simon ◽  
Karl Peters
Keyword(s):  
Michael Addition ◽  
Diastereoselective Synthesis

Diastereoselective Synthesis of CF3-Containing Vicinal Diamines

2017 ◽  
Vol 82 (15) ◽  
pp. 8273-8281 ◽  
Author(s):  
Qiu-xia Huang ◽  
Qu-tong Zheng ◽  
Yaya Duan ◽  
Jin-Hong Lin ◽  
Ji-Chang Xiao ◽  
...  
Keyword(s):  
Diastereoselective Synthesis ◽  
Vicinal Diamines

Diastereoselective synthesis of pitavastatin calcium via bismuth-catalyzed two-component hemiacetal/oxa-Michael addition reaction

2015 ◽  
Vol 13 (38) ◽  
pp. 9813-9819 ◽  
Author(s):  
Fangjun Xiong ◽  
Haifeng Wang ◽  
Lingjie Yan ◽  
Lingjun Xu ◽  
Yuan Tao ◽  
...  
Keyword(s):  
Asymmetric Synthesis ◽  
Michael Addition ◽  
Addition Reaction ◽  
Diastereoselective Synthesis ◽  
Michael Addition Reaction ◽  
Two Component ◽  
Pitavastatin Calcium

An efficient and concise asymmetric synthesis of pitavastatin calcium (1) starting from commercially available (S)-epichlorohydrin is described.

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