ABCB5+ dermal mesenchymal stromal cells with favorable skin homing and local immunomodulation for recessive dystrophic epidermolysis bullosa treatment

Julia Riedl; Michael Pickett-Leonard; Cindy Eide; Mark Andreas Kluth; Christoph Ganss; Natasha Y. Frank; Markus H. Frank; Christen L. Ebens; Jakub Tolar

doi:10.1002/stem.3356

ABCB5+ dermal mesenchymal stromal cells with favorable skin homing and local immunomodulation for recessive dystrophic epidermolysis bullosa treatment

Stem Cells ◽

10.1002/stem.3356 ◽

2021 ◽

Vol 39 (7) ◽

pp. 897-903 ◽

Cited By ~ 1

Author(s):

Julia Riedl ◽

Michael Pickett-Leonard ◽

Cindy Eide ◽

Mark Andreas Kluth ◽

Christoph Ganss ◽

...

Keyword(s):

Mesenchymal Stromal Cells ◽

Epidermolysis Bullosa ◽

Stromal Cells ◽

Dystrophic Epidermolysis Bullosa ◽

Skin Homing ◽

Recessive Dystrophic Epidermolysis Bullosa

329 Subcutaneous transplantation of allogenic mesenchymal stromal cells ameliorates intractable ulcers in recessive dystrophic epidermolysis bullosa patients

Journal of Investigative Dermatology ◽

10.1016/j.jid.2017.02.345 ◽

2017 ◽

Vol 137 (5) ◽

pp. S56

Author(s):

K. Tamai ◽

Y. Kikuchi ◽

L. Zhang ◽

Y. Komurasaki ◽

T. Yamaoka ◽

...

Keyword(s):

Mesenchymal Stromal Cells ◽

Epidermolysis Bullosa ◽

Stromal Cells ◽

Dystrophic Epidermolysis Bullosa ◽

Subcutaneous Transplantation ◽

Recessive Dystrophic Epidermolysis Bullosa

Study to evaluate the use of allogeneic mesenchymal stromal cells for the treatment of skin disease in children with recessive dystrophic epidermolysis bullosa

http://isrctn.org/> ◽

10.1186/isrctn46615946 ◽

2012 ◽

Author(s):

John Alexander McGrath

Keyword(s):

Mesenchymal Stromal Cells ◽

Epidermolysis Bullosa ◽

Stromal Cells ◽

Skin Disease ◽

Dystrophic Epidermolysis Bullosa ◽

Recessive Dystrophic Epidermolysis Bullosa

319 First-in-human treatment of recessive dystrophic epidermolysis bullosa with adipose derived mesenchymal stromal cells. A case report

Journal of Investigative Dermatology ◽

10.1016/j.jid.2019.07.320 ◽

2019 ◽

Vol 139 (9) ◽

pp. S269

Author(s):

R. Maseda ◽

L. Martínez-Santamaría ◽

R. Sacedón ◽

N. Butta ◽

S. García-Barcenilla ◽

...

Keyword(s):

Case Report ◽

Mesenchymal Stromal Cells ◽

Epidermolysis Bullosa ◽

Stromal Cells ◽

Dystrophic Epidermolysis Bullosa ◽

Recessive Dystrophic Epidermolysis Bullosa

Replenishment of type VII collagen and re-epithelialization of chronically ulcerated skin after intradermal administration of allogeneic mesenchymal stromal cells in two patients with recessive dystrophic epidermolysis bullosa

Cytotherapy ◽

10.3109/14653241003587637 ◽

2010 ◽

Vol 12 (3) ◽

pp. 429-431 ◽

Cited By ~ 105

Author(s):

Paulette Conget ◽

Fernando Rodriguez ◽

Susanne Kramer ◽

Carolina Allers ◽

Valeska Simon ◽

...

Keyword(s):

Mesenchymal Stromal Cells ◽

Epidermolysis Bullosa ◽

Stromal Cells ◽

Dystrophic Epidermolysis Bullosa ◽

Type Vii Collagen ◽

Intradermal Administration ◽

Recessive Dystrophic Epidermolysis Bullosa

Faculty Opinions recommendation of Intradermal injection of bone marrow mesenchymal stromal cells corrects recessive dystrophic epidermolysis bullosa in a xenograft model.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.733237172.793548160 ◽

2018 ◽

Author(s):

Dimitra Kiritsi

Keyword(s):

Bone Marrow ◽

Mesenchymal Stromal Cells ◽

Epidermolysis Bullosa ◽

Stromal Cells ◽

Xenograft Model ◽

Intradermal Injection ◽

Dystrophic Epidermolysis Bullosa ◽

Recessive Dystrophic Epidermolysis Bullosa

Intradermal Injection of Bone Marrow Mesenchymal Stromal Cells Corrects Recessive Dystrophic Epidermolysis Bullosa in a Xenograft Model

Journal of Investigative Dermatology ◽

10.1016/j.jid.2018.04.028 ◽

2018 ◽

Vol 138 (11) ◽

pp. 2483-2486 ◽

Cited By ~ 8

Author(s):

Clarisse Ganier ◽

Matthias Titeux ◽

Sonia Gaucher ◽

Juliette Peltzer ◽

Marc Le Lorc’h ◽

...

Keyword(s):

Bone Marrow ◽

Mesenchymal Stromal Cells ◽

Epidermolysis Bullosa ◽

Stromal Cells ◽

Xenograft Model ◽

Intradermal Injection ◽

Dystrophic Epidermolysis Bullosa ◽

Recessive Dystrophic Epidermolysis Bullosa

131 Phase I/II efficacy and safety study of mesenchymal stromal cells in recessive dystrophic epidermolysis bullosa

Journal of Investigative Dermatology ◽

10.1016/j.jid.2019.07.135 ◽

2019 ◽

Vol 139 (9) ◽

pp. S236

Author(s):

L. Martínez-Santamaría ◽

R. Maseda ◽

M. García ◽

E. Chacón-Solano ◽

S. García-Barcenilla ◽

...

Keyword(s):

Phase I ◽

Mesenchymal Stromal Cells ◽

Epidermolysis Bullosa ◽

Stromal Cells ◽

Efficacy And Safety ◽

Safety Study ◽

Dystrophic Epidermolysis Bullosa ◽

Recessive Dystrophic Epidermolysis Bullosa

Faculty Opinions recommendation of Replenishment of type VII collagen and re-epithelialization of chronically ulcerated skin after intradermal administration of allogeneic mesenchymal stromal cells in two patients with recessive dystrophic epidermolysis bullosa.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.4066956.3839054 ◽

2010 ◽

Author(s):

Yasushi Hanakawa

Keyword(s):

Mesenchymal Stromal Cells ◽

Epidermolysis Bullosa ◽

Stromal Cells ◽

Dystrophic Epidermolysis Bullosa ◽

Type Vii Collagen ◽

Intradermal Administration ◽

Recessive Dystrophic Epidermolysis Bullosa

Human Mesenchymal Stromal Cells Engineered to Express Collagen VII Can Restore Anchoring Fibrils in Recessive Dystrophic Epidermolysis Bullosa Skin Graft Chimeras

Journal of Investigative Dermatology ◽

10.1016/j.jid.2019.05.031 ◽

2020 ◽

Vol 140 (1) ◽

pp. 121-131.e6 ◽

Cited By ~ 4

Author(s):

Anastasia Petrova ◽

Christos Georgiadis ◽

Roland A. Fleck ◽

Leanne Allison ◽

John A. McGrath ◽

...

Keyword(s):

Mesenchymal Stromal Cells ◽

Skin Graft ◽

Epidermolysis Bullosa ◽

Stromal Cells ◽

Dystrophic Epidermolysis Bullosa ◽

Human Mesenchymal Stromal Cells ◽

Recessive Dystrophic Epidermolysis Bullosa ◽

Collagen Vii

Mesenchymal stromal cells in wound healing applications: role of the secretome, targeted delivery and impact on recessive dystrophic epidermolysis bullosa treatment

Cytotherapy ◽

10.1016/j.jcyt.2021.06.004 ◽

2021 ◽

Author(s):

Julia Riedl ◽

Courtney Popp ◽

Cindy Eide ◽

Christen Ebens ◽

Jakub Tolar

Keyword(s):

Wound Healing ◽

Mesenchymal Stromal Cells ◽

Epidermolysis Bullosa ◽

Stromal Cells ◽

Targeted Delivery ◽

Dystrophic Epidermolysis Bullosa ◽

Recessive Dystrophic Epidermolysis Bullosa