INHIBITORY EFFECT OF MAST CELL-MEDIATED IMMEDIATE-TYPE ALLERGIC REACTIONS BY CICHORIUM INTYBUS

1999 ◽  
Vol 40 (1) ◽  
pp. 61-65 ◽  
Author(s):  
HYUNG MIN KIM ◽  
HYE WON KIM ◽  
YEOUNG SU LYU ◽  
JIN HEE WON ◽  
DAE KI KIM ◽  
...  
2000 ◽  
Vol 22 (3) ◽  
pp. 489-500 ◽  
Author(s):  
Tae-Yong Shin ◽  
Sang-Hyun Kim ◽  
Sung-Hwa Kim ◽  
Yung-Kwon Kim ◽  
Hae-Jeong Park ◽  
...  

2004 ◽  
Vol 26 (2) ◽  
pp. 233-242 ◽  
Author(s):  
Ho‐Jeong Na ◽  
Phil‐Dong Moon ◽  
Seung‐Heon Hong ◽  
Jo‐Young Shin ◽  
Hyung‐Min Kim

1998 ◽  
Vol 55 (7) ◽  
pp. 1071-1076 ◽  
Author(s):  
Hyung-Min Kim ◽  
Eun-Hee Lee ◽  
Hye-Hyoung Cho ◽  
Young-Hoe Moon

2000 ◽  
Vol 22 (2) ◽  
pp. 253-266 ◽  
Author(s):  
Hyung-Min Kirn ◽  
Nyeon-Hyoung An ◽  
Byung-Hui Yi ◽  
Han-Jung Chae ◽  
Hyung-Ryong Kim ◽  
...  

2002 ◽  
Vol 24 (4) ◽  
pp. 583-594 ◽  
Author(s):  
Hye-Young Shin ◽  
Yeo-Bin Yun ◽  
Jeong-Yun Kim ◽  
Goo Moon ◽  
Tae-Yong Shin ◽  
...  

1999 ◽  
Vol 27 (03n04) ◽  
pp. 377-386 ◽  
Author(s):  
H. M. Kim ◽  
Y. H. Lee ◽  
H. J. Chae ◽  
H. R. Kim ◽  
S. H. Baek ◽  
...  

Shini-San has been used for treatment of allergic disease in Korea. However, its effect in experimental models remains unknown. The mast cell plays a pivotal role in initiating allergic response by secreting intracytoplasmic granular mediators such as histamine. The present report describes an inhibitory effect of Shini-San on mast cell-mediated immediate-type allergic reactions. Topical application of compound 48/80 can induce an ear swelling response in normal (WBB6F1-+/+) mice but not in congenic mast cell-deficient WBB6F1-W/Wvmice. Shini-San inhibited concentration-dependent mast cell-dependent ear swelling response induced by compound 48/80 in normal mice. Shini-San inhibited concentration-dependent passive cutaneous anaphylaxis induced by anti-dinitrophenyl (DNP) immunoglobulin E (IgE) in rats by topical application. Shini-San also inhibited in concentration-dependent fashion the histamine release from the rat peritoneal mast cells by compound 48/80 or anti-DNP IgE. Moreover, Shini-San had a significant inhibitory effect on compound 48/80-induced systemic anaphylactic reaction. These results indicate that Shini-San inhibits immediate-type allergic reactions by inhibition of mast cell degranulation in vivo and in vitro.


Author(s):  
Pratibha Gaur ◽  
Fidan Rahimli Alekberli ◽  
Laila Karra ◽  
David Mankuta ◽  
Micha Ben Zimra ◽  
...  

2001 ◽  
Vol 23 (1) ◽  
pp. 107-117 ◽  
Author(s):  
H. J. Jeong ◽  
H. N. Koo ◽  
N. I. Myung ◽  
M. K. Shin ◽  
J. W. Kim ◽  
...  

2016 ◽  
Vol 6 (2) ◽  
pp. 14.1-14.5
Author(s):  
Ka-Jung Ryu ◽  
Myeong-Sook Yoou ◽  
Kun-Young Park

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