scholarly journals A Japanese Adult Case of Guanidinoacetate Methyltransferase Deficiency

Author(s):  
Tomoyuki Akiyama ◽  
Hitoshi Osaka ◽  
Hiroko Shimbo ◽  
Tomoshi Nakajiri ◽  
Katsuhiro Kobayashi ◽  
...  

2012 ◽  
Vol 51 (5) ◽  
pp. 503-506 ◽  
Author(s):  
Shingo Koyama ◽  
Toru Kawanami ◽  
Shigeki Arawaka ◽  
Manabu Wada ◽  
Takeo Kato


2010 ◽  
Vol 49 (12) ◽  
pp. 1251-1252 ◽  
Author(s):  
Hiroaki Oka ◽  
Hiroshi Ishii ◽  
Kenji Kishi ◽  
Atsushi Yokoyama ◽  
Kosaku Komiya ◽  
...  






2021 ◽  
Vol 9 (8) ◽  
Author(s):  
Mounia Bendari ◽  
Hanane Delsa ◽  
Nouama Bouanani ◽  
Rajaa Jabouri ◽  
Safaa Darouich ◽  
...  




Author(s):  
Ai Jun Peng ◽  
Shu Cai Fan ◽  
Ya Xing Chen ◽  
Jian Han Huang ◽  
Yi Cao ◽  
...  


Open Medicine ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. 204-210 ◽  
Author(s):  
Yumi Ichikawa ◽  
Masato Murata ◽  
Makoto Aoki ◽  
Jun Nakajima ◽  
Yuta Isshiki ◽  
...  

AbstractA 62-year-old male who was receiving prednisolone and methotrexate for scleroderma and rheumatoid arthritis complained of diarrhea and vomiting, and was transferred to our hospital for detailed examination and treatment of renal dysfunction and thrombocytopenia. Hemolytic anemia and crushed erythrocytes were found during the patient’s course; therefore, we suspected thrombotic microangiopathy (TMA). His ADAMTS13 activity was 60.3% and his ADAMTS13 inhibitor was under 0.5. In addition, his blood culture was positive for Streptococcus pneumoniae, and we finally diagnosed Streptococcus pneumoniae-associated TMA (pTMA). The patient was treated with antibiotics and hemodialysis. The patient recovered and was discharged on the 45th hospital day. Adult pTMA cases are remarkably rare. We herein report a successfully treated adult case of pTMA.



2008 ◽  
Vol 11 (3) ◽  
pp. 252-257 ◽  
Author(s):  
Fumi Hayashi ◽  
Nobuo Yoshiike ◽  
Katsushi Yoshita ◽  
Kazuo Kawahara

AbstractObjectiveThere is an increasing concern of anaemia in Japanese women, but no national trend data has existed to date. We analysed long-term national trends of anaemia in adult women.DesignSecondary analyses of 15 consecutive cross-sectional nationwide surveys conducted during the period 1989–2003. Analyses were based on 5-year intervals (1989–1993, 1994–1998, 1999–2003).SettingJapan.SubjectsThe subjects included the National Health and Nutrition Survey of Japan (NHNS-J) population. Analyses were based on 50 967 non-pregnant/non-lactating women aged 20 years and over, with complete data sets. We stratified subjects into six age groups (20–29 years, 30–39 years, 40–49 years, 50–59 years, 60–69 years and 70+ years), and three age groups (20–49 years, 50–69 years, 70+ years) for analyses on residential areas (metropolitan, cities and towns).ResultsDecreases in trends of mean haemoglobin values (intravenous) were significant in all age groups. Changes in the prevalence of anaemia were significant only in women aged 30–39 and 40–49 years. Anaemia (haemoglobin < 12.0 g dl−1) increased from 16.8% to 20.6% in women aged 30–39 years, and from 20.2% to 26.9% in women aged 40–49 years, respectively. Prevalence was highest in women aged 70 years and older in all times, but no significant change was observed.ConclusionsHaemoglobin values have declined significantly in all ages in the last 15 years. Anaemia was especially significant in women aged 30–39 years and 40–49 years. Our findings suggest that a large number of young women in Japan are at risk of anaemia, so continuous monitoring and controlling efforts of this trend are needed.



Author(s):  
Ritsuto Fujiwaki ◽  
Hiroshi Miura ◽  
Akira Endo ◽  
Naoki Yoshino ◽  
Osamu Iwanari ◽  
...  
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