Management of End-Stage Liver Disease and the Role of Liver Transplantation in HIV-Infected Patients

2011 ◽  
pp. 171-179
Author(s):  
Marion G. Peters ◽  
Peter G. Stock
Keyword(s):  
Liver Transplantation ◽  
Liver Disease ◽  
End Stage Liver Disease ◽  
End Stage

Liver transplantation for children with biliary atresia in the pediatric end-stage liver disease era: The role of insurance status

2013 ◽  
Vol 19 (5) ◽  
pp. 543-550 ◽  
Author(s):  
Ronen Arnon ◽  
Rachel A. Annunziato ◽  
Asha Willis ◽  
Meera Parbhakar ◽  
Jaime Chu ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Disease ◽  
Biliary Atresia ◽  
Insurance Status ◽  
End Stage Liver Disease ◽  
End Stage

scholarly journals Predicting early allograft failure and mortality after liver transplantation: The role of the postoperative model for end-stage liver disease score

2013 ◽  
Vol 19 (5) ◽  
pp. 534-542 ◽  
Author(s):  
Gebhard Wagener ◽  
Brian Raffel ◽  
Andrew T. Young ◽  
Moury Minhaz ◽  
Jean Emond
Keyword(s):  
Liver Transplantation ◽  
Liver Disease ◽  
Disease Score ◽  
End Stage Liver Disease ◽  
Allograft Failure ◽  
End Stage

scholarly journals The Role of Interventional Radiology in Treating Complications following Liver Transplantation

2013 ◽  
Vol 2013 ◽  
pp. 1-6
Author(s):  
Homoyoon Mehrzad ◽  
Kamarjit Mangat
Keyword(s):  
Liver Transplantation ◽  
Interventional Radiology ◽  
Liver Disease ◽  
Surgical Technique ◽  
Diagnostic Tests ◽  
Pediatric Patients ◽  
Management Options ◽  
End Stage Liver Disease ◽  
End Stage

Liver transplantation (LT) is used to treat both adult and pediatric patients with end-stage liver disease or acute liver failure. It has become more prevalent as both the surgical technique and postoperative care have improved resulting in a reduced morbidity and mortality. As a result, there are more patients surviving longer after liver transplantation. Despite this, there remain serious complications from the procedure that have a significant outcome on the patient and may result in retransplantation. At the same time, there have been significant advances in the field of interventional radiology both in terms of technology and how these apply to the patients. In this paper, we review the commonest complications, diagnostic tests, and interventional management options available.

Management of end stage liver disease (ESLD): What is the current role of orthotopic liver transplantation (OLT)?

2006 ◽  
Vol 44 ◽  
pp. S140-S145 ◽  
Author(s):  
J MIRO ◽  
M LAGUNO ◽  
A MORENO ◽  
A RIMOLA ◽  
THEHOSPITALCLINICOLTINHIVWO
Keyword(s):  
Liver Transplantation ◽  
Liver Disease ◽  
Orthotopic Liver Transplantation ◽  
Current Role ◽  
End Stage Liver Disease ◽  
End Stage

scholarly journals Multicentric evaluation of model for end-stage liver disease-based allocation and survival after liver transplantation in Germany - limitations of the ‘sickest first’-concept

2010 ◽  
Vol 24 (1) ◽  
pp. 91-99 ◽  
Author(s):  
Tobias J. Weismüller ◽  
Panagiotis Fikatas ◽  
Jan Schmidt ◽  
Ana P. Barreiros ◽  
Gerd Otto ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Disease ◽  
End Stage Liver Disease ◽  
End Stage

Low psoas muscle index as an unfavorable factor in children with end‐stage liver disease undergoing liver transplantation

2021 ◽  
Author(s):  
Settapong Jitwongwai ◽  
Chatmanee Lertudomphonwanit ◽  
Thitiporn Junhasavasdikul ◽  
Praman Fuangfa ◽  
Pornthep Tanpowpong ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Disease ◽  
Psoas Muscle ◽  
End Stage Liver Disease ◽  
End Stage

scholarly journals RIPK3-Mediated Necroptosis and Neutrophil Infiltration Are Associated with Poor Prognosis in Patients with Alcoholic Cirrhosis

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Zhenzhen Zhang ◽  
Guomin Xie ◽  
Li Liang ◽  
Hui Liu ◽  
Jing Pan ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Disease ◽  
Poor Prognosis ◽  
Alcoholic Cirrhosis ◽  
Normal Liver ◽  
Neutrophil Infiltration ◽  
Meld Score ◽  
End Stage Liver Disease ◽  
Cirrhotic Patients ◽  
End Stage

Alcoholic cirrhosis is an end-stage liver disease with impaired survival and often requires liver transplantation. Recent data suggests that receptor-interacting protein kinase-3- (RIPK3-) mediated necroptosis plays an important role in alcoholic cirrhosis. Additionally, neutrophil infiltration is the most characteristic pathologic hallmark of alcoholic hepatitis. Whether RIPK3 level is correlated with neutrophil infiltration or poor prognosis in alcoholic cirrhotic patients is still unknown. We aimed to determine the correlation of RIPK3 and neutrophil infiltration with the prognosis in the end-stage alcoholic cirrhotic patients. A total of 20 alcoholic cirrhotic patients subjected to liver transplantation and 5 normal liver samples from control patients were retrospectively enrolled in this study. Neutrophil infiltration and necroptosis were assessed by immunohistochemical staining for myeloperoxidase (MPO) and RIPK3, respectively. The noninvasive score system (model for end-stage liver disease (MELD)) and histological score systems (Ishak, Knodell, and ALD grading and ALD stage) were used to evaluate the prognosis. Neutrophil infiltration was aggravated in patients with a high MELD score (≥32) in the liver. The MPO and RIPK3 levels in the liver were positively related to the Ishak score. The RIPK3 was also significantly and positively related to the Knodell score. In conclusion, RIPK3-mediated necroptosis and neutrophil-mediated alcoholic liver inflammatory response are highly correlated with poor prognosis in patients with end-stage alcoholic cirrhosis. RIPK3 and MPO might serve as potential predictors for poor prognosis in alcoholic cirrhotic patients.

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