Science and Technology of Pressurized Metered-Dose Inhalers

2011 ◽  
pp. 165-201 ◽  
Author(s):  
Sandro R. P. da Rocha ◽  
Balaji Bharatwaj ◽  
Sowmya Saiprasad
Keyword(s):  
Science And Technology ◽  
Metered Dose Inhalers ◽  
Metered Dose ◽  
Pressurized Metered Dose Inhalers

scholarly journals Design of Pressurized Metered Dose Inhalers Modeling of Internal Flow and Atomization

2010 ◽  
Vol 4 (2) ◽  
Author(s):  
Henk Versteeg ◽  
Abdul Qaiyum Shaik
Keyword(s):  
Experimental Work ◽  
Equilibrium Model ◽  
Lung Diseases ◽  
Internal Flow ◽  
Flow Conditions ◽  
Metered Dose Inhalers ◽  
Numerical Predictions ◽  
Metered Dose ◽  
Flow Through ◽  
Pressurized Metered Dose Inhalers

Pressurized metered-dose inhalers (pMDIs) have been the most effective therapeutic treatment for controlling lung diseases such as asthma and COPD. The flow through a two-orifice system of pMDI is very complex and poorly understood. Previous experimental work has shown that metastability may play a significant role in determining the flow conditions inside pMDIs. In this paper, we present the findings of a homogeneous equilibrium model with those of a delayed equilibrium model (DEM) accounting for propellant metastability. These results are compared with the available experimental and numerical predictions Further, the DEM was applied with HFA propellants R134A and R227, and the results were compared with traditional propellant R12.

scholarly journals Imperative Instruction for Pressurized Metered-Dose Inhalers: Provider Perspectives

2018 ◽  
Vol 64 (3) ◽  
pp. 292-298
Author(s):  
Daniel C Schmitz ◽  
Rebecca A Ivancie ◽  
Kyung E Rhee ◽  
Heather C Pierce ◽  
Alicia O Cantu ◽  
...  
Keyword(s):  
Metered Dose Inhalers ◽  
Provider Perspectives ◽  
Metered Dose ◽  
Pressurized Metered Dose Inhalers

scholarly journals Consequences of not-shaking and shake-fire delays on the emitted dose of some commercial solution and suspension pressurized metered dose inhalers

2020 ◽  
Vol 17 (7) ◽  
pp. 1025-1039
Author(s):  
Veronica Chierici ◽  
Luca Cavalieri ◽  
Alessio Piraino ◽  
Davide Paleari ◽  
Eride Quarta ◽  
...  
Keyword(s):  
Metered Dose Inhalers ◽  
Metered Dose ◽  
Emitted Dose ◽  
Pressurized Metered Dose Inhalers
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