Tension and Intracellular Calcium Transients of Activated Ferret Ventricular Muscle in Response to Step Length Changes

1993 ◽  
pp. 639-648 ◽  
Author(s):  
Yasutake Saeki ◽  
Satoshi Kurihara ◽  
Kenichi Hongo ◽  
Etsuko Tanaka
Keyword(s):  
Intracellular Calcium ◽  
Step Length ◽  
Calcium Transients ◽  
Ventricular Muscle ◽  
Length Changes

Caffeine attenuates contraction-induced diminutions of the intracellular calcium transient in mouse lumbrical muscle ex vivo

2019 ◽  
Vol 97 (5) ◽  
pp. 429-435 ◽  
Author(s):  
Ian C. Smith ◽  
Rene Vandenboom ◽  
A. Russell Tupling
Keyword(s):  
Skeletal Muscle ◽  
Intracellular Calcium ◽  
Calcium Release ◽  
Ex Vivo ◽  
Calcium Transient ◽  
Calcium Transients ◽  
Inotropic Effects ◽  
Intracellular Calcium Transient ◽  
Lumbrical Muscle ◽  
Lumbrical Muscles

The amount of calcium released from the sarcoplasmic reticulum in skeletal muscle rapidly declines during repeated twitch contractions. In this study, we test the hypothesis that caffeine can mitigate these contraction-induced declines in calcium release. Lumbrical muscles were isolated from male C57BL/6 mice and loaded with the calcium-sensitive indicator, AM-furaptra. Muscles were then stimulated at 8 Hz for 2.0 s in the presence or absence of 0.5 mM caffeine, at either 30 °C or 37 °C. The amplitude and area of the furaptra-based intracellular calcium transients and force produced during twitch contractions were calculated. For each of these measures, the values for twitch 16 relative to twitch 1 were higher in the presence of caffeine than in the absence of caffeine at both temperatures. We conclude that caffeine can attenuate contraction-induced diminutions of calcium release during repeated twitch contractions, thereby contributing to the inotropic effects of caffeine.

Tilting of the light-chain region of myosin during step length changes and active force generation in skeletal muscle

Nature ◽  
1995 ◽  
Vol 375 (6533) ◽  
pp. 688-691 ◽  
Author(s):  
Malcolm Irving ◽  
Taylor St Claire Alien ◽  
Cibele Sabido-David ◽  
James S. Craik ◽  
Birgit Brandmeier ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Light Chain ◽  
Step Length ◽  
Force Generation ◽  
Active Force ◽  
Length Changes ◽  
Active Force Generation

Morphine coupling to invertebrate immunocyte nitric oxide release is dependent on intracellular calcium transients

1999 ◽  
Vol 123 (3) ◽  
pp. 295-299 ◽  
Author(s):  
Fernando E Nieto-Fernandez ◽  
Dwight Mattocks ◽  
Francesco Cavani ◽  
Michel Salzet ◽  
George B Stefano
Keyword(s):  
Nitric Oxide ◽  
Intracellular Calcium ◽  
Calcium Transients ◽  
Nitric Oxide Release

scholarly journals Distinct Intracellular Calcium Transients in Neurites and Somata Integrate Neuronal Signals

2002 ◽  
Vol 22 (13) ◽  
pp. 5344-5353 ◽  
Author(s):  
Friedrich W. Johenning ◽  
Michal Zochowski ◽  
Stuart J. Conway ◽  
Andrew B. Holmes ◽  
Peter Koulen ◽  
...  
Keyword(s):  
Intracellular Calcium ◽  
Calcium Transients
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