Borderline personality disorder (BPD) is routinely encountered in all clinical settings and has been stigmatized and perceived as a difficult disorder to manage. Over the past 25 years, significant gains in our understanding of the diagnosis, treatment, and outcomes of the disorder have helped improve the lives of these patients. BPD is now understood to begin in adolescence and early adulthood, with a generally positive course and reductions in symptoms of self-harm and suicidality within several years of diagnosis. BPD is best understood as developing through an interaction between genetic and environmental factors. No clear biological features have been consistently identified yet, and similarly, no clear psychosocial factor, including childhood adversity or sexual abuse, is causative for BPD. Clearly separating BPD from other disorders, particularly bipolar disorder, is an important consideration and required to ensure proper care. Comorbid disorders, including other personality disorder, are frequent problems that partially reflect a challenge with the current diagnostic system that has not yet been resolved. Although the symptomatic outcome of patients with BPD is very good, functional outcomes, such as holding work and relationships, is more challenging for many patients, and suicide remains a risk in patients with this disorder.
This review contains 2 figures, 4 tables, and 102 references.
Key words: borderline personality disorder, outcome, personality disorder, self-harm, suicide