Mucosal Antibody Responses to HIV

2009 ◽  
pp. 333-345 ◽  
Author(s):  
Zina Moldoveanu ◽  
Jiri Mestecky
Keyword(s):  
Antibody Responses ◽  
Mucosal Antibody

scholarly journals The immune landscape of IgA induction in the gut

2021 ◽  
Author(s):  
Claudia Seikrit ◽  
Oliver Pabst
Keyword(s):  
Protective Immunity ◽  
Immunoglobulin A ◽  
Antibody Responses ◽  
Dark Side ◽  
Secretory Immunoglobulin A ◽  
Antibody Isotype ◽  
Mucosal Antibody ◽  
Key Concepts ◽  
Basic Understanding ◽  
Secretory Immunoglobulin

AbstractAntibodies are key elements of protective immunity. In the mucosal immune system in particular, secretory immunoglobulin A (SIgA), the most abundantly produced antibody isotype, protects against infections, shields the mucosal surface from toxins and environmental factors, and regulates immune homeostasis and a peaceful coexistence with our microbiota. However, the dark side of IgA biology promotes the formation of immune complexes and provokes pathologies, e.g., IgA nephropathy (IgAN). The precise mechanisms of how IgA responses become deregulated and pathogenic in IgAN remain unresolved. Yet, as the field of microbiota research moved into the limelight, our basic understanding of IgA biology has been taking a leap forward. Here, we discuss the structure of IgA, the anatomical and cellular foundation of mucosal antibody responses, and current concepts of how we envision the interaction of SIgA and the microbiota. We center on key concepts in the field while taking account of both historic findings and exciting new observations to provide a comprehensive groundwork for the understanding of IgA biology from the perspective of a mucosal immunologist.

scholarly journals Vaccination Strategies to Promote Mucosal Antibody Responses

Immunity ◽  
2010 ◽  
Vol 33 (4) ◽  
pp. 479-491 ◽  
Author(s):  
Kang Chen ◽  
Andrea Cerutti
Keyword(s):  
Antibody Responses ◽  
Vaccination Strategies ◽  
Mucosal Antibody

Salmonella typhi Ty21a bacterial ghost vector augments HIV-1 gp140 DNA vaccine-induced peripheral and mucosal antibody responses via TLR4 pathway

Vaccine ◽  
2012 ◽  
Vol 30 (39) ◽  
pp. 5733-5739 ◽  
Author(s):  
Jing Wen ◽  
Yi Yang ◽  
Guangyu Zhao ◽  
Shuang Tong ◽  
Hong Yu ◽  
...  
Keyword(s):  
Dna Vaccine ◽  
Salmonella Typhi ◽  
Antibody Responses ◽  
Mucosal Antibody ◽  
Bacterial Ghost ◽  
Hiv 1

Comparison of serum and mucosal antibody responses following severe acute rotavirus gastroenteritis in young children.

1988 ◽  
Vol 26 (4) ◽  
pp. 732-738 ◽  
Author(s):  
K Grimwood ◽  
J C Lund ◽  
B S Coulson ◽  
I L Hudson ◽  
R F Bishop ◽  
...  
Keyword(s):  
Young Children ◽  
Antibody Responses ◽  
Rotavirus Gastroenteritis ◽  
Mucosal Antibody

Experimental infection of calves with Newcastle disease virus induces systemic and mucosal antibody responses

2008 ◽  
Vol 153 (6) ◽  
pp. 1197-1200 ◽  
Author(s):  
Madhuri Subbiah ◽  
Yongqi Yan ◽  
Daniel Rockemann ◽  
Siba K. Samal
Keyword(s):  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Experimental Infection ◽  
Newcastle Disease ◽  
Antibody Responses ◽  
Mucosal Antibody

scholarly journals Morphine Inhibits Mucosal Antibody Responses and TGF-β mRNA in Gut-Associated Lymphoid Tissue Following Oral Cholera Toxin in Mice

2001 ◽  
Vol 167 (7) ◽  
pp. 3677-3681 ◽  
Author(s):  
Xiaohui Peng ◽  
John J. Cebra ◽  
Martin W. Adler ◽  
Joseph J. Meissler ◽  
Alan Cowan ◽  
...  
Keyword(s):  
Cholera Toxin ◽  
Lymphoid Tissue ◽  
Antibody Responses ◽  
Mucosal Antibody

scholarly journals Repeated vaginal administration of trimeric HIV-1 clade C gp140 induces serum and mucosal antibody responses

2009 ◽  
Vol 3 (1) ◽  
pp. 57-68 ◽  
Author(s):  
M P Cranage ◽  
C A Fraser ◽  
Z Stevens ◽  
J Huting ◽  
M Chang ◽  
...  
Keyword(s):  
Antibody Responses ◽  
Vaginal Administration ◽  
Mucosal Antibody ◽  
Clade C ◽  
Hiv 1
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