Ultrastructure of the effect of T-514 obtained from Karwinskia humboldtiana on assembly and integrity of yeast's peroxisomes

1991 ◽  
Vol 49 ◽  
pp. 136-137
Author(s):  
J. Sepulveda-Saavedra ◽  
I. Vander-Klei ◽  
M. Venhuis ◽  
Y. Piñeyro-Lopez
Keyword(s):  
Culture Conditions ◽  
Toxic Effects ◽  
Candida Boidinii ◽  
Central Mexico ◽  
Poisonous Plant ◽  
Biological Behaviour ◽  
Enzyme Content ◽  
Fat Deposits ◽  
Yeast Model

Karwinskia humboldtiana is a poisonous plant that grows in semi desertic areas in north and central México. It produces several substances with different toxic effects. One of them designated T-514 damages severely the lung, kidney and liver, producing in the hepatoeyte large intracellular fat deposits and necrosis. Preliminary observations demonstrated that three is a decrease in the amount of peroxisomes in the hepatocytes of experimentally intoxicated rats and monkeys. To study the effect exerted by the T-514 on peroxisomes, a yeast model was selected, thus, three species: Saccha romices cerevisiae, Ilansenula polymorpha and Candida boidinii were used, because there is information concerning their peroxisome's morphology, enzyme content, biological behaviour under different culture conditions and biogenesis.

Aggregating Welfare Indicators into an Operational Welfare Assessment System: A Bottom-up Approach

2001 ◽  
Vol 51 (2) ◽  
pp. 53-57 ◽  
Author(s):  
Tine Rousing ◽  
Marianne Bonde ◽  
Jan Tind Sørensen
Keyword(s):  
Assessment System ◽  
Bottom Up ◽  
Welfare Assessment ◽  
Welfare Indicators ◽  
System A

Psychology and Culture: Top Down Versus Bottom Up?

PsycCRITIQUES ◽  
2005 ◽  
Vol 50 (19) ◽  
Author(s):  
Michael Cole
Keyword(s):  
Top Down ◽  
Bottom Up

Top-down vs. bottom-up: When instructions overcome automatic retrieval

2011 ◽  
Author(s):  
A. Kiesel ◽  
F. Waszak ◽  
R. Pfister
Keyword(s):  
Top Down ◽  
Bottom Up ◽  
Automatic Retrieval

Counting Broken Causal Links: A Pattern-Based Heuristic Model of Bottom-Up Causal Induction

2008 ◽  
Author(s):  
Ralf Mayrhofer ◽  
York Hagmayer ◽  
Michael R. Waldmann
Keyword(s):  
Heuristic Model ◽  
Bottom Up ◽  
Causal Induction

Top-Down and Bottom-Up Control of Oculomotor Responses in Dual Tasks

2014 ◽  
Author(s):  
Aleksandra Pieczykolan ◽  
Lynn Huestegge
Keyword(s):  
Top Down ◽  
Dual Tasks ◽  
Bottom Up ◽  
Oculomotor Responses
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